News to Use

  • Two building projects to be completed in coming weeks with dedication ceremonies

    The IU School of Medicine will celebrate the completion of two major construction projects in the coming weeks.

    A dedication for Lyles-Porter Hall Health and Human Sciences Building at 715 Clinic Dr., West Lafayette, Ind., will be at 4:30 p.m. Friday, Sept. 26, and a dedication celebration for the IUSM Neurosciences Research Building, located 320 W. 15th St., Indianapolis, will be at 3:30 p.m. Wednesday, Oct. 1.

    The $54-million Lyles-Porter Hall, the first building in the Life and Health Sciences Park on the Purdue University campus, is the new site of the IU School of Medicine-Lafayette. The $52-million IUSM Neuroscience Research Building, at 138,000 square feet, together with the adjacent IU Health Neuroscience Center, at 270,000 square feet, will create a hub of expertise in neurosciences for researchers, doctors, patients and future physicians in training.

    Lyles-Porter Hall is named in honor of a $10 million 2009 gift from Marybeth Lyles-Porter Higuera of Visalia, Calif., a former speech pathologist who earned her bachelor’s degree in speech-language pathology at Purdue in 1959. Additional facilities in the space will include the Purdue Department of Speech, Language and Hearing Sciences and other health-related clinical, educational and research spaces.

    The neurosciences research building has been designed make flexible research space available to interdisciplinary research teams with a disease focus, rather than assigning space according to traditional academic departments. The exterior of the building features an efficient skin primarily of glass that both provides natural light inside and support efforts to obtain LEED (Leadership in Energy and Environmental Design) Silver Certification.

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  • Registration open for the Indiana CTSI Sixth Annual Meeting

    The Indiana Clinical and Translational Sciences Institute Sixth Annual Meeting, "From Academic Centers to Population Health," will be from 7:30 a.m. to 3 p.m. Friday, Sept. 26, at the Hine Hall Auditorium at IUPUI.

    IUSM speakers and panelists include Jay L. Hess, M.D., Ph.D., MHSA, dean of the Indiana University School of Medicine and vice president for university clinical affairs at IU; Brad Doebbeling, M.D., professor of medicine and professor and chair of the School of Informatics and Computing at IUPUI; William M. Tierney, M.D., associate dean for clinical effectiveness research and president and CEO of the Regenstreif Institute; Lisa Harris, M.D., associate dean for Eskenazi Health Affairs and CEO of Eskenazi Health; Michael Weiner, M.D., associate professor of medicine and director of health services research and development for the Richard L. Roudebush VA Medical Center; and Sarah Wiehe, M.D., associate professor of pediatrics and co-director of the Indiana CTSI Community Health Engagement Program.

    Additional speakers include IUPUI Chancellor Charles R. Bantz, Ph.D., who will deliver the welcome, and Paul K. Halverson, Dr.Ph., dean of the IU Richard M. Fairbanks School of Public Health at IUPUI.

    Anyone from the Indiana CTSI member institutions of IU, Purdue University and the University of Notre Dame are welcome to attend. This is a free event and lunch is included. 

    To RSVP, visit the registration page. Questions to info@indianactsi.org.

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Research News

  • IU researchers find combining epilepsy drug, morphine can result in less pain, lower opioid doses

    Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects, as well as reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at IU whose research has been reported in the journal PLOS ONE.

    In laboratory tests conducted in rodents, IU researchers found that while morphine lost its pain-relieving effectiveness three weeks after nerve injury, a combination therapy of morphine and carbamazepine -- used to prevent epileptic seizures -- could effectively reverse this loss of drug action. Although morphine and related opioid drugs are effective in treating pain, they can result in dependence and produce side effects including respiratory depression, nausea, constipation and other problems. Combining the two drugs could prevent the escalating doses of opioids that are sometimes prescribed to provide pain relief in the clinic. The result could bring significant relief to many patients with neuropathic pain, a difficult-to-treat condition often felt in the arms and legs and associated with nerve tissue damage.

    Both drugs are approved for use by the Food and Drug Administration. Fletcher White, Ph.D., Vergil K. Stoelting Professor of Anesthesia at the IU School of Medicine and an author on the study, recently began testing the combination of morphine and a close relative of carbamazepine with patients in a small clinical trial at the IU Simon Cancer Center.

    In addition to Dr. White, IUSM authors on the paper include Michael R. Due, Xiao-Fang Yang, Yohance M. Allette, Aaron L. Randolph, Matthew S. Ripsch, Sarah M. Wilson and Erik T. Dustrude. Other contributors include Rajesh Khanna of the University of Arizona. The research was funded by National Institutes of Health grants NIDDK DK100905 and NIDA DA026040 and the Indiana Spinal Cord and Brain Injury Research Fund.

    For more information, visit the IUSM Newsroom.

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  • Indiana CTSI awards pilot, equipment and commercialization grants

    The Indiana Clinical and Translational Sciences Institute awarded about $250,000 this summer to support clinical and translational research projects at IU, Purdue and Notre Dame. Funded projects include research focused on breast cancer, traumatic brain injury, anti-viral drug development and neuroimaging of smokers' e-cigarette use decisions.

    The funds stem from three grant programs. The Core Pilot Grant program, which provides pilot funds to access labs, technology and expertise at Indiana CTSI-designed cores; the Core Equipment Grant program, which supports the purchase of new lab equipment and technologies; and Research Invention and Scientific Commercialization, or "RISC," grants, which support research with high future potential to spin off into new companies and technologies. IU School of Medicine recipients are:

    • 2014 Spring Core Pilot Grant Awardees: Carmella Evans-Molina, M.D., Ph.D., assistant professor of medicine; Brittney-Shea Herbert, Ph.D., associate professor of medical and molecular genetics; Jenifer Prosperi, Ph.D., assistant professor of biochemistry and molecular biology; Andrew Saykin, Psy.D., Raymond C. Beeler Professor of Radiology; and Kenneth White, Ph.D., David D. Weaver professor of medical and molecular genetics.
    • Core Equipment Grant Awardees: Kenneth W. Dunn, Ph.D., associate professor of medicine and biochemistry; Charles R. Tessier, Ph.D., research assistant professor of medical and molecular genetics at IUSM-South Bend; Karen E. Pollok, Ph.D., assistant professor of pediatrics; and Jamie Case, Ph.D., assistant research professor of pediatrics.
    • Research Invention and Scientific Commercialization Awardees: Hiroki Yokota, Ph.D., adjunct professor of anatomy and cell biology; and Jian-Ting Zhang, Ph.D., Andrew and Peggy Thomson Chair in Hematology/Oncology and professor of pharmacology and toxicology

    For a complete list of awardees and their project titles, including recipients from other schools at IUPUI and IU Bloomington, see the Indiana CTSI website.

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Faculty and Staff News

  • Haggstrom to co-lead cancer control and prevention research

    David Haggstrom, M.D., has been named co-leader of the Cancer Prevention and Control research program at the IU Simon Cancer Center.

    Dr. Haggstrom is an associate professor of medicine at the IU School of Medicine and a research scientist at the Regenstrief Institute and VA Center for Health Information and Communication. He is the founding director of the IUPUI Center for Cancer Population Analytics and Patient-Centered Informatics.

    His research focuses upon reducing the burden of cancer through health services research and population-based approaches to health care delivery, as well as promoting patient-centered care through medical informatics. He has clinical research interests in the quality of medical and surveillance care among cancer survivors. With support from the Livestrong Foundation, he has developed a survivorship care plan/personal health record for colorectal cancer survivors.

    Prior to joining the faculty at IU, he completed a postdoctoral fellowship at the NCI and earned a master’s of clinical research from the University of California, San Francisco. While at IU, he has been named a VA/Robert Wood Johnson Physician Faculty Scholar.

    Dr. Haggstrom succeeds Victoria Champion, Ph.D., who remains the associate director of population science at the IU Simon Cancer Center.

    Dr. Haggstrom joins Jiali Han, Ph.D., as co-leader of the program. Dr. Han is the Rachel Cecile Efroymson Professor in Cancer Research at the IU School of Medicine and professor and chair of the Department of Epidemiology at the IU Richard M. Fairbanks School of Public Health.

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Opportunities

  • Distinguished Professorships and Teaching Award nominations sought

    The IUSM community is encouraged to nominate faculty to honor their outstanding teaching, research and service. School-wide faculty awards due Wednesday, Oct. 15, include:

    • Excellence in Faculty Mentoring Awards: This underscores the school's commitment to endorse mentoring among our faculty, which is a crucial element in sustaining a vital faculty community, promoting faculty development, and increasing faculty retention. These awards recognize the outstanding mentoring efforts of one clinician and one basic scientist each year that actively mentor other faculty members and learners.
    • Inspirational Educator Award: This award recognize faculty who inspire learners and motivate them to work hard and achieve more than they thought possible on their own. It acknowledges the time and dedication faculty take to be exceptional teachers.
    • Outstanding Community Engagement Award: The Faculty Community Relations Committee Award for Outstanding Community Engagement was established to recognize and encourage exceptional community engagement by IUSM faculty in activities such as, but not limited to, volunteerism, community based learning or research, outreach, partnerships and curricular engagement.
    • Scholar Educator Award: This award recognizes faculty who go beyond simply teaching and approach education in scholarly manner. It acknowledges faculty who approach teaching and learning from a scholarly lens.

    In addition, IUSM also seeks nominations for two endowed awards (external recipients only) by Friday, Nov. 7:

    • Steven C. Beering Award for Advancement of Biomedical Science: This award honors an internationally recognized individual for outstanding research contributions to the advancement of biomedical or clinical science. Past recipients of this award, established in 1984, include six Nobel Prize winners.
    • Mark Brothers Award: This award recognizes nationally and internationally renowned medical scientists of Asian descent. This award was established by Dr. and Mrs. Guey C. Mark in 1997 in honor of Dr. Mark’s brothers, who immigrated from Canton and settled in South Bend, Ind., where they established a successful restaurant business.

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  • Stress Management Workshop free to full-time IUPUI employees

    Full-time IUPUI employees and their spouses/partners on an IU medical plan are eligible to attend a free session on stress management.

    "A Guide to Less Stress" will take place from 11:30 a.m. to 12:30 p.m. Thursday, Sept. 25, in the IUPUI Campus Center, Room 307.

    Participants will learn about the effects of stress on the mind and body, techniques to manage and reduce stress, and resources available through IU to help keep stress in check -- such as the Employee Assistance Program.

    "This program is in response to what you said in the Fairbanks School of Public Health’s Workplace Wellness Survey -- 70 percent of employees say that stress is affecting their health and 40 percent are not getting enough social and emotional support . . . from any source," said Patty Hollingsworth, director of Healthy IU, IU’s workplace wellness program. "The survey also indicated many employees are not aware of the resources available at IUPUI."

    The session is presented by John Nolan, LCSW, CISM, who has over 20 years of experience in the field of mental wellbeing and is well-versed in the IU Employee Assistance Program.

    Registration is required. To sign up, visit the Healthy IU’s Registration Portal and make sure to select IUPUI’s campus.

    For more well-being resources, visit IUPUI’s Healthy IU page.

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Kudos

  • Fellow selected for prestigious training program

    Heather O'Leary, Ph.D., a postdoctoral fellow at the IU of Indiana University School of Medicine, has been selected to participate in the Translational Research Training in Hematology Program.

    O'Leary is one of only 20 junior hematologists chosen to participate in this joint program of the American Society of Hematology and European Hematology Association, which provides junior researchers from around the world with a unique, year-long training and mentoring experience that aims to help early-career scientists build successful translational hematology research careers.

    The 20 junior researchers selected to participate in the 2014 Translating Research Training in Hematology Program first completed a rigorous week-long training course featuring didactic and interactive sessions led by some of the world’s leading hematology and translational researchers on translational research methodology and regulatory requirements.

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  • IUSM-based journal earns high impact factor

    "Brain Imaging and Behavior," a journal based in the IU School of Medicine Department of Radiology and Imaging Sciences, recently achieved an impact factor of 3.385 with 527 citations in 2013.

    The rise in impact over the past several years is a significant achievement for a relatively new journal founded in 2007, said Andrew J. Saykin, O.D., director of the Center for Neuroimaging and Raymond C. Beeler Professor of Radiology at the IU School of Medicine, who serves as editor-in-chief of the journal.

    Editorial board members of the journal at IUSM include Amit Anand, M.D., adjunct professor of psychiatry; David Kareken, Ph.D., Professor of neurology and clinical psychology; Thomas McAllister, M.D., chair and Sterne Professor of Clinical Psychiatry; and Brenna McDonald, O.D., associate professor of radiology and imaging and neurology.

    IU faculty, staff and fellows (past and present) who have authored or co-authored papers or provided peer reviews are Diane Von Ah, Ph.D.; Dr. Anand; Daniel Albrecht; Carol Baird, Ph.D.; Alan Breier, M.D.; Susan Conroy; Ulrike Dydak, Ph.D.; Mario Dzemidzic, Ph.D.; Martin Farlow, M.D.; Tatiana Foroud, Ph.D.; Sujuan Gao, Ph.D.; Andrew Goddard, M.D.; Meredith Golomb, M.D.; Joaquin Goni, Ph.D.; Kelly Holohan; Leslie Hulvershorn, M.D.; Thomas Hummer, Ph.D.; Andrew Kalnin, M.D.; Dr. Kareken; Michelle Keiski, P.h.D.; Sungeun Kim, Ph.D.; William Kronenberger, Ph.D.; Brandy Matthews, M.D.; and Kristine Marie Mosier, Ph.D.

    Also, Dr. McAllister; Dr. McDonald; Dawn Neumann, Ph.D.; Alexander Niculescu, M.D., Ph.D.; Vijay Ramanan, Ph.D.; Shannon Risacher, Ph.D.; Yong Shin; Kimberly Ann Stigler, M.D.; Yang Wang, M.D.; John West, M.S.; Donald Wong, Ph.D.; Xiaogang Wu; Yu-Chien Wu, M.D., Ph.D.; Karmen Yoder, Ph.D.; and Elizabeth Zauber, M.D.

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