Faculty and Staff News
Scientists respond to opioid crisis through innovative research
It’s no secret that the United States is in the midst of a debilitating opioid misuse crisis with no clear end in sight. According to the Centers for Disease Control and Prevention (CDC), more than 42,000 lives were claimed as a result of opioid use in 2016 alone with 40 percent of these deaths involving at least one prescribed opioid.
Scientists at IU School of Medicine are working to change the trajectory of the epidemic. Under the direction of Brady Atwood, PhD, assistant professor of psychiatry, researchers have identified a link between opioid receptors and a recently identified brain circuit that may produce addictive behaviors. Opioid receptors are proteins that control one’s responses to opioid use. They also serve as regulators of how different parts of the brain communicate or “talk” to one another.
“What we have found is that just one single exposure to a prescription opioid can produce changes in the brain that last for days,” Atwood explained.
In addition to the interference of normal communication within the brain that results from opioid use, their newest study shows that alcohol consumption has a very similar impact on the way opioid receptors operate.
“Opioid and alcohol exposure prevents these receptors from controlling communication between two parts of the brain--one of which controls the brain’s perception of the body, and the other controls habitual behaviors,” said Atwood. “What was especially fascinating was that these effects were very specific to the connection between these two parts of the brain. As we start to understand how these two parts of the brain communicate with each other and the effect that opioids and alcohol have on this communication, we can begin to identify new targets for treatment.”
IU Simon Cancer Center awarded National Cancer Institute funds to expand smoking cessation treatment
Indiana University Melvin and Bren Simon Cancer Center is one of 22 centers nationwide chosen for a federally funded initiative to reduce tobacco use by cancer patients. The two-year, $500,000 grant from the National Cancer Institute is for the Cancer Center Cessation Initiative--an initiative created to expand existing efforts at NCI-designated cancer centers to assist patients who are smokers to quit using tobacco.
Indiana ranks high nationally for its rate of tobacco use and elevated incidence of tobacco-related cancers. To reduce the incidence and morbidity of tobacco-related cancers, the IU Simon Cancer Center is partnering with the Purdue University College of Pharmacy, IU School of Nursing and Indiana University Health, as well as community pharmacies throughout the state.
Co-leaders of the Cancer Center Cessation Initiative are cancer center members Karen Hudmon, DrPH, professor of pharmacy practice at Purdue University and adjunct assistant professor of medicine at IU School of Medicine, and Lisa Carter-Harris, PhD, assistant professor of nursing at IU School of Nursing. Additional core team members include co-investigator DuyKhanh Ceppa, MD, assistant professor of cardiothoracic surgery at IU School of Medicine and a thoracic surgeon at IU Health, and program director Deborah Hudson, tobacco cessation specialist at the IU Simon Cancer Center.
Ultimately, the goal is to reach patients statewide through IU Health clinics and community pharmacists, who in 2017 received legislative authority expanding their ability to provide FDA-approved medications for smoking cessation with assistance and follow-up care.
Dr. Peipert focusing efforts on OB/GYN department growth
It’s been two years since Jeffrey Peipert, MD, PhD, joined IU School of Medicine as chair for the Department of Obstetrics and Gynecology. Since then, the department has welcomed more than a dozen new faculty members and increased its number of research studies to more than 30. Dr. Peipert said that’s just the beginning.
“We’re starting to see a real swing in terms of morale, in terms of momentum,” said Dr. Peipert, “and I’ve very excited about the next three to five years ahead.”
Learn more about Dr. Peipert and his vision for the department in this Faculty News blog post.
Get your CrimsonCard before June 30
If you haven’t replaced your current IU School of Medicine ID with a CrimsonCard, make plans to do it soon. All current IU School of Medicine students, faculty and staff (part time and full time), and affiliates, including residents and fellows, must replace current school ID cards with IU’s university-wide CrimsonCard before June 30. All current JagTag and IU School of Medicine ID cards will stop working on this date.
The details you need to know are included in a list of frequently asked questions, including information for colleagues at regional campuses.
Here is how to get started on the Indianapolis campus:
Step 1: Visit the CrimsonCard (formerly JagTag) office in the IUPUI Campus Center or Informatics & Communications Technology Complex to get a CrimsonCard. Be sure to tell the representative you need the IU School of Medicine multi-function card (also called the triple-technology card).
Step 2: If you use your ID to access IU Health facilities, email your CrimsonCard information to IU Health. (Read FAQ for specifics.)
Step 3: Hold onto your old ID, because access to IU Health buildings will not immediately transfer to your CrimsonCard.
March research awards total over $3.4 million
Investigator Sponsor Type Project Title Begin Date End Date Awarded Dollars Micheala A. Aldred National Heart, Lung And Blood Institute New Genomics of Pulmonary Vascular Disease 4/1/18 3/31/19 777,434 Cynthia Diane Brown Cystic Fibrosis Foundation Therapeutics Inc. Renewal (not prev committed) Additional Research Coordinator (ARC) Award 12/1/17 11/30/18 42,920 Linda A DiMeglio University Of South Florida Renewal (not prev committed) Safety & Efficacy of Imatinib for Preserving Beta-cell Function in New-onset Type 1 Diabetes Mellitus 10/1/17 9/30/18 4,100 Linda A DiMeglio Johns Hopkins University Renewal (not prev committed) P1084s Endocrinologist for IMPAACT 12/1/17 11/30/18 1,313 Martin Rhys Farlow Washington University New Dominantly Inherited Alzheimer Network Trial 6/1/17 12/31/17 70,637 Brett H Graham Riley Children's Foundation New Models of Complex I Deficiency are Translational Tools for Leigh Syndrome 1/2/18 1/1/19 50,000 Debra Hickman U.s. Department Of Veterans Affairs Renewal (not prev committed) VA Contract for Vet IPA and other LARC Services 4/1/18 3/31/19 275,154 Barry P. Katz University Of Michigan New Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings 9/11/17 7/31/18 62,760 Mark R. Kelley National Cancer Institute Renewal (not prev committed) Exploiting the Ref-1 node in pancreatic cancer: tailoring new pancreatic cancer therapy using multi-targeted combinations 3/9/18 2/28/19 493,726 R Michael Meneghini Medical University Of South Carolina New Comparative Effectiveness of Pulmonary Embolism Prevention after Hip and Knee Replacement (PEPPER): Balancing Safety and Effectiveness 1/1/18 2/28/18 16,614 Raghu G Mirmira Riley Children's Foundation New Wm & Helen Thomas Trust 1/1/18 8/31/18 25,000 Bruce A. Molitoris University Of Mississippi Medical Center New Novel Roles of Mitochondrial Angiotensin II in The Proximal Tubule of the Kidney 9/21/17 8/31/18 85,896 Brian Heath Mullis Saint Louis University New Early weight bearing on supracondylar distal femur fractures in elderly patients 2/15/18 12/31/18 2,000 Christie M Orschell National Institute Allergy & Infectious Diseases New Extending the scope of PLX-R18 for H-ARS: efficacy in special populations and DEARE 3/8/18 2/28/19 528,607 Alexander G Robling National Institute Arthritis Musculoskeletal Skin New In vivo discovery of the osteocyte protein secretome: identification of novel factors and functions 3/1/18 2/28/19 393,750 Thomas M Rouse Boston Children's Hospital New A Multicenter Trial of Contrast-Enhanced Ultrasound in the Evaluation of Abdominal Solid Organ Injuries in Pediatric Trauma Patients 2/13/18 2/12/21 34,000 Andrew Lawrence Schwaderer National Institute Of Diabetes, Digestive & Kidney New The interface between critical acid-base mediators and the renal bacterial defense 4/1/18 3/31/19 152,961 Robert S. Tepper Oregon Health & Science University New VCSIP2:CCC - Lead Application 6/19/17 5/31/18 419,126 Bree Ashley Weaver Health And Hospital Corporation Of Marion County Renewal (not prev committed) Midwest AIDS Training and Education Center (MATEC) Program 7/1/17 6/30/18 13,228 Mervin C. Yoder University Of Alabama Birmingham New Human iPSC for repair of vasodegenerative vessels in diabetic retinopathy? 7/1/17 1/31/18 26,386
Faculty and Staff News
Spring Faculty Meeting is May 1
The IU School of Medicine Spring Faculty Meeting will be held from 4:30-6 pm, Tuesday, May 1, in Walther Hall (R3) Auditorium, Room C203. Faculty meetings are held twice a year to discuss issues of importance to IU School of Medicine. Topics that will be covered at this meeting include:
- IU School of Medicine 2018 Trustee Teaching Award recipients recognition -- Paul Wallach, MD, executive associate dean for educational affairs and institutional improvement
- IU School of Medicine 2018 faculty election results -- Brittney-Shea Herbert, PhD, associate professor of medical & molecular genetics, Faculty Steering Committee (FSC) president-elect
- Faculty Steering Committee update -- Dan Rusyniak, MD, professor of emergency medicine, FSC president
- Education, curriculum and GME expansion update -- Paul Wallach, MD, executive associate dean for educational affairs and institutional improvement
- Highlighted discoveries by IU School of Medicine faculty -- Anantha Shekhar, MD, PhD, executive associate dean for research affairs
- Strategic planning update -- Steve Bogdewic, PhD, executive vice dean of IU School of Medicine
- Dean’s update -- Jay Hess, MD, PhD, dean, IU School of Medicine
A question and answer session will follow; submit questions prior to the meeting. The FSC encourages all faculty to attend in person. For those who are unable, the meeting will be available via live web stream and teleconference. Instructions for participating remotely are posted on the Faculty Steering Committee webpage. A video recording will be available on the webpage after the meeting.
April 24 “Academic Life Hacks” to focus on time management
Managing clinical duties, academic scholarship and personal life is a part of faculty life at an academic medical center. Learn tips and shortcuts for juggling the various aspects of an academician’s life at “Academic Life Hacks” from 5-7 pm, Tuesday, April 24, in Fairbanks Hall, Rooms 1109/1111.
Registration is available. The session is part of the Faculty Enrichment Education Development (FEED) series and is sponsored by the Office of Faculty Affairs and Professional Development.
Register for May 3 Wellness Symposium
Finding balance and developing resiliency while working in medicine will be discussed at the 2018 Wellness Symposium on Thursday, May 3, in Hine Hall on the IUPUI campus. The symposium will feature these presentations:
Finding Meaning, Balance and Personal Satisfaction in the Practice of Medicine
11:30 am-1 pm, Hine Hall Auditorium
A pioneer in research focused on physician burnout, Tait Shanafelt, MD, chief wellness officer, Stanford Medicine, will review the literature on physician satisfaction and burnout, discuss data on the repercussions of physician distress, and highlight personal and organizational approaches to promote physician well-being. Register for this presentation.
Creating a Professional Toolkit for Resilience and Well-Being: An Experiential Session
1:30-3 pm, Hine Hall (IP) 132
Hedy Wald, PhD, will discuss resilience and well-being-enhancement strategies, including mindful awareness, reflective writing as a “resiliency workout,” cognitive restructuring, positive psychology principles and meaning-making/purpose. Register for this presentation.
The Wellness Symposium is sponsored by the IU School of Medicine Department of Family Medicine; Faculty Affairs, Professional Development and Diversity; and IU Health Physicians.
Students inducted into Lambda Nu National Honor Society
Eight students in the IU School of Medicine Radiologic & Imaging Science Program were inducted into Lambda Nu, the national honor society for radiologic and imaging sciences. The students, honored at a ceremony earlier this month, are the second group to be inducted in the Lambda Nu Indiana PSI Chapter, which was established last fall.
Students inducted in April are:
Students inducted in November 2017 are:
Class of 2020: Take the S3 to earn $2,500 for your class
Thanks to student feedback, IU School of Medicine has made numerous improvements in the student experience, including implementing pass/fail grading, providing earlier clinical exposure and improving access to course evaluations. By taking the Strategic Student Survey (S3), the Class of 2020 can provide input for future improvements. In addition, if 80 percent of the class completes the survey by Sunday, April 22, the school will contribute $2,500 for Match Day, Senior Banquet or commencement expenses.
Attend inaugural student research symposium this Saturday
The first IU School of Medicine Student Research Symposium will be held from noon-3 pm, Saturday, April 21, in the Van Nuys Medical Science Building Atrium. A student-led effort, the event will showcase students’ research and scholarly projects. Questions? Email firstname.lastname@example.org.
April 23 is deadline to register for Senior Awards Program
The IU School of Medicine Senior Awards Program will be held at 5 pm, Friday, May 11, at The Crane Bay in downtown Indianapolis. The event celebrates graduating students and recognizes faculty and staff for their contributions to students’ medical education. The event is free for Class of 2018 members, but registration is required. Guest tickets may be purchased for $30 each. Deadline to register and purchase tickets is Monday, April 23.
MS4: Commencement parking is free for completing the GQ
In addition to contributing to the medical student experience and earning the chance to win great prizes, the Class of 2018 now has one more reason to complete the Graduation Questionnaire (GQ)--free commencement parking. If 80 percent of the Class of 2018 completes the GQ by Wednesday, May 2, every student in the class will receive a parking pass to use for the Saturday, May 12, commencement. Get more details on current completion rate and how to qualify for prizes.
MS4: Check out the commencement tutorial
Tam, tassel, hood--check, check, check. You’ve ordered what you need for commencement, now view this graduation tutorial for important do’s and don’ts. The IU School of Medicine Commencement ceremony will be held from 9:30-11:30 am, Saturday, May 12, in the Sagamore Ballroom of the Indiana Convention Center in downtown Indianapolis. Doors open at 8 am, and graduating students should be lined up no later than 8:30 am. Tickets are not required for guests; however, seats cannot be reserved.
Faculty to speak at Stepping Stones of Women in Leadership events
The Stepping Stones of Women in Leadership series is for faculty and students to learn about professional development from hearing the personal career journeys of successful women. Upcoming series events include presentations by two IU School of Medicine faculty members:
Project funding available for addiction care technologies
Indiana University School of Medicine and the Purdue University College of Engineering aim to develop addiction care technologies that are well suited not only for the deterrence and monitoring of vulnerable patient populations in clinical settings, but also the rapidly increasing opioid epidemic on the streets.
Applications to this program are limited to faculty from IU School of Medicine and the Purdue College of Engineering with a total budget of $100,000 ($50,000 per campus). Eligibility requirements and application details are available. Deadline to apply is Friday, June 1.
Apply for funds to advance surgical and interventional care
Funding is available to develop potential devices in the broad areas of surgery and surgical intervention. Investigators are encouraged to propose innovative ideas that can result in a device that improves human health. Successful collaborations will involve at least two investigators from two different Indiana Clinical and Translational Sciences Institute campuses and will represent surgical and/or interventional expertise with human patients and device expertise.
Application deadline is Friday, June 1. Application details are available.
HANDS in Autism Art Expo is April 26-27
Celebrate Autism Awareness Month at the eighth annual HANDS in Autism Art Expo, “Worth a Thousand Words,” on Thursday, April 26 and Friday, April 27, in the Simon Family Tower Atrium at Riley Hospital for Children at Indiana University Health. The expo is designed to provide a glimpse into the perspectives of individuals with autism spectrum disorder (ASD) who use art as a means of expression given some of the social and communicative challenges that ASD presents. Meet the featured artists during the “An Evening of the Arts” event from 6:30-8:00 pm on April 26 or visit the expo on April 27 from 9 am-4 pm. Admission is free.
Last day to register: Indiana CTSI Bloomington Retreat
Today is the last day to register for the Indiana CTSI Bloomington Retreat, “Science as a Solution to Indiana’s Opioid Crisis,” on Wednesday, April 25, on the IU Bloomington campus. Free and open to the public, the retreat offers valuable opportunities to network with investigators from across the state and learn more about research resources and services available through the Indiana CTSI. Speakers from IU, the state of Indiana, Johns Hopkins, Columbia University and the National Institutes of Health will be featured.
Riley construction underway
Wheels are officially in motion for the Riley Maternity and Newborn Health strategic building project. First steps include relocating the People Mover door near the cafeteria to allow for other construction work that lies ahead.
Here’s what to expect this month:
- This week – circle driveway on Barnhill Avenue closes to all traffic; fencing and interior dust walls go up; Atrium Lobby closes
- Week of April 23 – glass elevators no longer accessible; pedestrian traffic rerouted to silver elevators
The building project will take two years to complete. Expect foot traffic pattern changes, temporary signage and even some construction equipment on site as work continues.
Patient Safety and Quality Day oral presentation winners named
One IU School of Medicine fellow and two residents were named winners for their oral presentations during the third annual Patient Safety and Quality Day on April 6. The event is dedicated to advancing quality improvement and patient safety efforts by facilitating a collaboration between clinical leaders, providers, educators, trainees and students across multiple healthcare disciplines.
Emergency medicine-clinical informatics fellow
"One-click Integration of Information from the Indiana Network for Patient Care with Cerner"
Radiation oncology resident
"Retrospective vs Prospective Peer Review in a Multisite Academic Radiation Department"
Emergency medicine resident
"Identifying Palliative Care Needs in the Emergency Department"