Top News

  • 5 takeaways from Dean Hess’ presentation to the IU Board of Trustees

    Indiana University School of Medicine Dean Jay L. Hess, MD, PhD, MHSA, updated the IU Board of Trustees about the state of the school on Thursday, October 4, outlining significant progress made over the last several years and highlighting the school’s mission to make Indiana one of the nation’s healthiest states.

    Read the Strategic Voices blog post for details on these five takeaways from the dean’s presentation:

    • Diversity among IU School of Medicine students is on the rise.
    • Research funding to the school continues to surge.
    • Donors are making significant investments in the school’s research and education missions.
    • Faculty are choosing IU School of Medicine.
    • The School of Medicine-led IU Precision Health Initiative is resulting in improved care for patients.

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  • Nominations sought for Watanabe Translational Research Prize

    Indiana University School of Medicine is accepting nominations for the 2019 August M. Watanabe Prize in Translational Research, awarded to an investigator who has made a significant contribution to the field of translational science.

    The Watanabe Prize is one of the nation’s largest and most prestigious awards recognizing individuals focused on shepherding scientific discoveries into new therapies for patients. It is named in honor of the late August M. Watanabe, a titan in the field of translational research in both academia and industry, who impacted the health of people around the world as a leader at IU and Eli Lilly and Co. Watanabe began his career at IU School of Medicine in 1972 and served as chair of the Department of Medicine from 1983 to 1990. From there, he joined Eli Lilly, where he was ultimately named executive vice president, overseeing the launch of 11 drugs and doubling the size of the company’s research and development staff.

    Nominees for the Watanabe Prize should be members of the scientific or medical community who have achieved outstanding accomplishments in translational research. This award is conferred upon senior investigators whose influential research deserves major recognition.

    The winner of the 2019 Watanabe Prize will receive a $100,000 award and spend time in Indianapolis as a visiting dignitary to share knowledge with audiences at IU and partner institutions. Over the next two years, the honoree also will serve as a long-distance mentor to two exceptional young investigators named concurrently as Watanabe Translational Scholars.

    Nomination deadline is Monday, January 28, 2019. Submission details and requirements are available. Email amwprize@iu.edu or call 317.278.2874 with questions.

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  • IU President McRobbie to deliver State of the University address on Tuesday

    Indiana University President Michael A. McRobbie will present the annual State of the University address at 1:30 pm, Tuesday, October 16, in President's Hall at Franklin Hall on the Indiana University Bloomington campus.

    McRobbie is expected to discuss the university's progress toward goals and initiatives outlined in the university's Bicentennial Strategic Plan and preparations for IU's bicentennial celebration in 2019-20.

    In keeping with the Faculty Constitution and IU tradition, the University Faculty Council invites the president to present a report on the state of the university each year. All members of the IU community and the general public are invited to view the address in person, via live-stream broadcasting at broadcast.iu.edu or on IU Bloomington Campus Cable Channel 51. There are other ways to view the address.

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  • Flu shot deadline is less than a month away

    Flu season is quickly approaching, and so is the deadline to receive a flu vaccination. All IU School of Medicine faculty, house staff and students who provide clinical care at Indiana University Health or Eskenazi Health, perform clinical research at these facilities or whose primary office is in an IU Health or Eskenazi Health hospital are required to receive a flu vaccination before Thursday, November 8. Flu shot outreach clinics are scheduled through Thursday, November 1.

    On the IUPUI campus, free flu shots are available at Campus Health (Coleman Hall, Suite 100) or at one of the flu outreach clinics listed below. Students (only) also may obtain a flu shot at Campus Center Student Health. Free flu vaccinations are also available for IU School of Medicine staff.

    Outreach clinic schedule (locations convenient to IU School of Medicine)
    Friday, October 12, 8 am-1 pm: Med Sciences South Atrium
    Thursday, October 18, 8 am-1 pm; Med Sciences South Atrium
    Tuesday, October 23, 2:30-4:30 pm; HITS Lobby
    Thursday, November 1, 9 am-3 pm; Health and Benefits Fair (CE 405)

    Flu vaccination information for other IU campuses is also available. 

     

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Research News

  • New study could change when women push during labor

    New research co-authored by an Indiana University School of Medicine faculty member could change the way women give birth.

    “The big question has been when a woman is in labor and the cervix is fully open, which is 10 centimeters, should the woman start pushing immediately to try to deliver the baby or should they wait for the baby’s head to come down before they start pushing?” said Methodius Tuuli, MD, MPH, professor of obstetrics and gynecology, vice chair of obstetrics and director of perinatal research at IU School of Medicine Department of Obstetrics and Gynecology.

    Tuuli joined IU School of Medicine in August 2018. He was previously a faculty member at Washington University in St. Louis where he co-authored a National Institute of Health-funded study focused on when women in labor should begin pushing.

    “The overarching challenge is that although pregnancy, labor and delivery is a very common process and physicians and other providers have been managing pregnancy and delivery for centuries, many aspects of how we manage labor and how we help women labor and deliver do not have evidence that tells us what to do.”

    Tuuli and the other authors, who are from several different institutions across the country, decided to study whether it’s best for women to begin pushing once they are fully dilated or to wait longer. Tuuli says when women give birth naturally and do not have an epidural, their bodies naturally start to push once they are fully dilated. For women who do have an epidural or some sort of pain management, they don’t feel as much, so they have to be coached on when to begin pushing.

    Read about the findings of the 2,400-woman study, which is the largest clinical trial on labor management in the field to date.

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  • Cancer researchers find new targets to alleviate anemia during chemotherapy

    It is not uncommon for patients with cancer to develop anemia based on a number of factors, including the type of cancer they have or stress induced by chemotherapy treatments. Anemia, which is caused by a lack of oxygen-delivering hemoglobin in the red blood cells, can be especially threatening to those with cancer. In addition to exacerbating feelings of weakness and fatigue, patients with both cancer and anemia may experience a delay or reduction in chemotherapy treatment.

    While there are successful treatments for anemia, its primary treatment option--known as erythropoietin, or EPO--remains ineffective in a number of anemic disorders. Among these disorders are Diamond Blackfan anemia and Fanconi anemia--two pediatric diseases for which there are no current treatments.

    Investigators at the Indiana University Melvin and Bren Simon Cancer Center and the Herman B Wells Center for Pediatric Research hope to change that. Learn more about their recent study and the breakthrough findings.

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  • September research awards total more than $18 million

    Investigator Sponsor Type Project Title Begin Date End Date Awarded Dollars
    Albany, Costantine University Of Illinois At Urbana-champaign New DNA Methylation Inhibitor Therapy for Testicular Cancer 5/1/2018 4/30/2019 85,000
    Bidwell, Joseph P. National Institute Arthritis Musculoskeletal Skin New The Nmp4 Anti-Anabolic Bone Axis R01AR070144-01A1 8/15/2018 7/31/2019 375,736
    Biswas, Naro National Hemophilia Foundation New Engineered regulatory T cell therapy for tolerance to FVIII 7/1/2018 6/30/2021 210,000
    Byrne, Bobbi J University Of Virginia New VentFirst: A multicenter RCT of assisted ventilation during delayed cord clamping for extremely preterm infants 4/1/2018 12/31/2018 31,500
    Clapp, D Wade Us Army Medical Research Acquisition Activity New Targeted Therapeutics for NF2 in a Pre-Clinical Model 8/15/2018 8/14/2021 905,626
    Clapp, D Wade Riley Children's Foundation Renewal (not prev committed) Haddad Scholars Program 7/1/2018 6/30/2019 100,000
    Clapp, D Wade Riley Children's Foundation Renewal (not prev committed) Research Scholars, Department of Pediatrics 7/1/2018 6/30/2019 500,000
    Dunnington, Gary L Riley Children's Foundation Renewal (not prev committed) James Joseph Harbaugh, Jr. Professor in Pediatric Plastic Surgery 7/1/2018 6/30/2019 25,581
    Elmendorf, Jeffrey S National Institute Of Diabetes, Digestive & Kidney New Cholesterol Toxicity as a Promising Target for Diabetes Prevention 8/22/2018 6/30/2019 388,254
    Ermel, Aaron Christopher Children's Hospital Medical Center Of Cincinnati New Fanconi Anemia as a Model for Susceptibility to Human Papillomavirus Infection 2/1/2017 12/31/2017 6,939
    Eugster, Erica A. Riley Children's Foundation New Diabetes Education Endowment Fund 7/1/2018 6/30/2019 111,966
    Evans-Molina, Carmella University Of Florida New Network for Pancreatic Organ Donors - nPOD 4/1/2018 3/31/2019 24,136
    Fogel, Evan L. National Institute Of Diabetes, Digestive & Kidney New Magnetic resonance Imaging as a Non-Invasive Method for Assessment of Pancreatic fibrosis (MINIMAP): a pilot study 9/20/2018 6/30/2019 715,410
    Foroud, Tatiana M Foundation For Peripheral Neuropathy Renewal (not prev committed) Peripheral Neuropathy Research Registry 12/1/2017 12/31/2018 70,342
    Guo, Haitao National Institute Allergy & Infectious Diseases New The Role of HBeAg in HBV Persistence 8/10/2018 7/31/2019 418,840
    Haas, David M Rti International Renewal (not prev committed) Pregnancy as a Window to Future Cardiovascular Health 5/1/2018 12/31/2018 17,399
    Hains, David (Nephro) Nationwide Children's Hospital Renewal (not prev committed) Rebuilding a Kidney Annotation Supplement 9/1/2017 8/31/2018 28,141
    Hains, David (Nephro) Ohio State University Renewal (not prev committed) Urine antimicrobial proteins in older adults: aging, infection, & innate immunity 6/1/2018 5/31/2019 101,153
    Herzog, Roland W Children's Hospital Of Philadelphia New Molecular and cellular mechanisms of the FVIII immune response (Project 2) 5/1/2018 4/30/2019 293,563
    Lai, Charly National Heart, Lung And Blood Institute New Role of Skeletal Muscle in Pulmonary Vascular Remodeling 8/15/2018 6/30/2019 437,850
    Lu, Xiongbin University Of Maryland New Nanotechnology enabled targeting of p53 deficiency in human cancer 7/1/2018 6/30/2019 180,112
    McAllister, Thomas W Us Army Medical Research Acquisition Activity New Cumulative and persistent intermediate effects of concussion and head impact exposure in CARE Consortium Military Service Academy members and NCAA Athletes. 9/1/2018 8/31/2020 9,992,700
    Motaganahalli, Raghu L Purdue University New Heat therapy for intermittent claudication 7/1/2018 5/31/2019 108,484
    Mullis, Brian Heath Johns Hopkins University Renewal (not prev committed) Transtibial Amputation Outcomes Study (TAOS): Comparing Transtibial Amputation with and without a Tibia-fibula Synostosis Procedure 4/1/2017 8/31/2019 20,624
    Natoli, Roman M Foundation For Orthopedic Trauma New Mitigating the effects of hemodynamic shock on fracture and muscle healing using non-selective systemic immunomodulation 8/1/2018 7/31/2020 20,000
    Neely, Daniel E. Salus University Renewal (not prev committed) Efficacy of Intermittent Occlusion in Amblyopia Treatment 4/1/2018 3/31/2019 6,781
    O'Neil, Kathleen M. East Tennessee State University New Healthcare Transition Readiness and Health Self-management among youth with Juvenile Systemic Lupus 1/2/2018 1/1/2019 3,858
    Pili, Roberto Us Army Medical Research Acquisition Activity New Therapeutic targeting TFE3 in translocation renal cell carcinoma 9/1/2018 8/31/2021 630,000
    Sadhasivam, Senthil Riley Children's Foundation Renewal (not prev committed) Stephen F. Dierdorf, M.D. Endowment Fund for Research in Pediatric Anesthesia - Grant #17-A40 7/1/2018 6/30/2019 5,184
    Sadhasivam, Senthil Riley Children's Foundation Renewal (not prev committed) Gopal Krishna FY19 Professorship in Pediatric Anesthesia 7/1/2018 6/30/2019 24,694
    Shin, Andrea Sunae Indiana University Health New Efficacy of psychological therapies in patients with functional bowel disorders with history of early adverse life events or post-traumatic stress disorder 8/1/2018 7/31/2021 150,000
    Smith, Jodi L Riley Children's Foundation New Seizure Surgery Multidisciplinary Program 4/1/2018 3/31/2019 10,000
    Stefanidis, Dimitrios Indiana University Health New Optimizing Healthcare Provider Performance: Mental Skills Training to Make Average Performance Excellent 8/1/2018 7/31/2020 100,000
    Stefanidis, Dimitrios American College Of Surgeons New Advanced Manikin Model (AMM) Program 9/26/2016 9/25/2019 60,000
    Territo, Paul R Jackson Laboratory New Improving Preclinical Translation in Alzheimer's Disease Research 9/1/2018 8/31/2019 5,233
    Weiss, Michael A. Case Western Reserve University New Design of Novel Insulin Analogs with Preferential Activity in White Adipose Tissue 12/15/2017 7/31/2018 8,418
    Weiss, Michael A. Case Western Reserve University New Glucose-Responsive Insulin Analogs 1/1/2018 6/30/2018 254,955
    White, Fletcher A Us Army Medical Research Acquisition Activity New CHRONIC HEADACHE DUE TO MILD TRAUMATIC BRAIN INJURY IN ADULTS: ALTERATIONS OF BRAIN FUNCTION, CENTRAL SENSITIZATION AND INFLAMMATORY PROCESSES 8/15/2018 8/14/2021 1,757,550
    Wiehe, Sarah Elizabeth Indiana State Department Of Health New 2018 Community Health Engagement Program Community-Based Research Pilot Project 11/1/2018 10/31/2019 105,000

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Faculty and Staff News

  • Faculty members receive awards at school’s fall meeting

    Several IU School of Medicine faculty members were honored for their accomplishments at the Fall Faculty Meeting on Tuesday, October 2. Winners of the following awards were announced.

    Excellence in Faculty Mentoring
    Basic Science: Claire E. Walczak, PhD
    Clinical: Sara Jo Grethlein, MD

    Inspirational Educator
    Over 10 Years: Michael House, MD
    Under 10 Years: W. Graham Carlos, MD

    Outstanding Community Engagement Award
    Deborah Hamby, MD

    Scholar Educator Award
    Gabriel Bosslet, MD

    Honoring outstanding teaching, research and service is an important part of IU School of Medicine’s culture.

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  • New faculty family leave policy approved

    The Indiana University Board of Trustees recently approved the changes put forth by the IU School of Medicine Faculty Steering Committee and adopted the revised version of Indiana University School of Medicine Paid Family Leave for Academic Appointees (ACA 51) policy effective August 10, 2018. This brings the school’s policy into greater alignment with the Indiana University Paid Family Leave for Academic Appointees (ACA 50), which governs academic appointees in all other IU schools. 

    The major changes to the IU School of Medicine Paid Family Leave policy are: 

    • Reduces the eligibility period from two years of full-time service to one year 
    • Aligns eligible family members for the purpose of consistency across all IU academic appointees
    • Requires family formation leave to conclude within six months
    • Separates paid family leave from paid medical leave. IU School of Medicine academic appointee sick leave is now covered under ACA 49--Other Leaves and Absences for Academic Appointees--and is now consistent with all other IU academic appointees
    With questions, contact your unit’s faculty affairs coordinator or Melody Darnall. With questions related to IU Health Physicians family and medical leaves for dually employed academic appointees, contact Barb Maple or Kristie Pruzin with IU Health Physicians Human Resources.

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  • Priority review deadline for behavioral health leadership position is November 4

    Applications are being accepted for a new behavioral health leadership position. The Indiana University School of Medicine Department of Psychiatry and Indiana University Health seek an innovative academic and clinical leader to serve as vice chair of clinical affairs and vice president of behavioral health collaborative. The selected individual will oversee departmental clinical operations and a statewide behavioral health system collaborative.

    Job description, qualifications and application information are available at Faculty Careers at IU. Priority review deadline is Sunday, November 4.

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Opportunities

  • Apply for Indiana CTSI young investigator awards by December 19

    The Indiana Clinical and Translational Sciences Institute (CTSI) seeks applicants for the CTSI Young Investigator Awards in Clinical-Translational Research. These awards provide promising junior investigator faculty an opportunity to be mentored in research-intensive multidisciplinary settings to develop careers in clinical-translational research. Clinical research includes epidemiological studies, clinical trials or other investigations involving human subjects.

    To be eligible, candidates must fall into one of the following categories: 

    • Clinician-scientists with a doctoral degree (physicians, nurses, dentists, pharmacists, clinical psychologists, optometrists, veterinarians, allied health care professionals, etc.)
    • Basic scientists with a PhD who are doing translational research that involves some component of human subjects research and has high potential for early translation in impacting patient care.
    Interested candidates must e-mail their CV to Patricia McGuire by Wednesday, December 19, for eligibility determination prior to submission of a full application online.

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  • Learn about and apply for predoctoral, postdoctoral training awards

    The Indiana Clinical and Translational Sciences Institute (CTSI) is offering special predoctoral and postdoctoral training awards in translational research. In biomedical terminology translational research refers to what is commonly termed "bench to bedside," the process by which research in the lab "translates" into patient treatment. Translation may involve applying discoveries made during research (in the lab, through animal studies, etc.) to the development of clinical trials and studies in humans, or carrying out research aimed at enhancing the adoption of best practices, or both.

    View eligibility and award information for predoctoral training awards.

    View eligibility and award information for postdoctoral training awards.

    Application deadlines are Thursday, November 15, for the predoctoral award and Monday, December 3, for the postdoctoral awards.

     

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  • Health law symposium to feature speaker Melissa Anderson

    Melissa Anderson, MD, assistant professor of clinical medicine, will participate in a panel discussion on healthcare rights as part of the Hall Center for Law and Health: Indiana Health Law Review Symposium, “The Intersection of Immigration Law and Public Policy.” The symposium, hosted by the IU Robert H. McKinney School of Law on the IUPUI campus, will be held on Friday, October 26. Agenda and registration details are available.

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  • Notre Dame to host Indiana CTSI retreat on October 26

    Researchers and the public are invited to attend the annual Indiana Clinical and Translational Sciences Institute (CTSI) retreat at the University of Notre Dame in South Bend, Indiana. The event will take place at Notre Dame’s McCourtney Hall on Friday, October 26, from 9 am - 4:15 pm EDT.

    Research teams will present on a variety of topics, including an overview of CTSI programs, global health, translational drug discovery, promoting collaborations and more. Additionally, attendees will be able to participate in poster presentations and attend panel discussions with drug discovery leaders who have university and industry backgrounds.

    This event is open to the public. All attendees who plan to present a poster are asked to register by Friday, October 12. Event registration will close on Friday, October 19.

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  • Heartland Film Festival to screen documentary about transplant pioneer

    A new documentary about liver transplant pioneer Thomas Starzl, MD, will be screened in October as part of the Heartland Film Festival.

    Marketing materials describe the documentary: In 1967, Dr. Thomas Starzl stunned the world with the first successful liver transplantation. His breakthrough provoked controversy. Critics accused him of recklessness, even murder. Others declared it the beginning of a medical revolution. Burden of Genius” is the story of an innovator as complex and elusive as the biological secrets he unlocked. It is also a reflection on the price of scientific progress by the man many consider the greatest surgeon of the 20th century and the father of transplantation.

    “Burden of Genius” screenings:
    Monday, October 15: 7:30 pm, The Toby at Newfields
    Friday, October 19: 10:45 am, AMC Castleton Square
    Saturday, October 20: 10:15 am, AMC Traders Point

    Purchase tickets with the discount code: BURDENHFF18. View a preview.  

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  • October 18 is deadline to apply for core facilities pilot funding

    The Indiana CTSI pilot funding program promotes the use of technologies and expertise afforded by the Indiana CTSI Core Facilities available at all partner institutions. Applications to this program should have a maximum requested amount of $10,000, and projects are typically two years in duration. 

    Funding is for use of designated Indiana CTSI core facilities only. Information describing each core is available. Pilot funding application deadline is Thursday, October 18.

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Partner News

  • Former IU Health leader Evans to receive IU Distinguished Alumni Service Award

    Daniel F. Evans, Jr., former CEO of Indiana University Health, is one of five Indiana University alumni receiving the university’s Distinguished Alumni Service Award today as part of IU’s homecoming weekend festivities.

    Serving as CEO of IU Health from 2002 to 2016, Evans oversaw its expansion into a statewide system of 18 facilities and increased revenue for the consortium from $850 million to over $5 billion. News at IU includes more on Evans and bios of the other four award winners.

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