Faculty and Staff News
Lasting Legacy: Tyler Trent on the importance of medical research
When Purdue University student Tyler Trent found out in May 2017 that his osteosarcoma had spread, he decided to help the Indiana University School of Medicine physician-scientists who helped treat him learn more about the aggressive bone cancer, which currently has no cure.
Trent, who died January 1 at age 20, was first diagnosed with osteosarcoma at age 15, when the cancer was found in his shoulder area. A few years later, when the cancer returned, he agreed to provide tissue samples from a tumor removed from his pelvis in hopes of prolonging other kids’ lives and motivating them to become advocates for research.
IU School of Medicine is keeping Trent’s memory alive by sharing his thoughts on the importance of participating in research and how genomic sequencing helped to prolong his life. View the video and read the blog post.
Osteosarcoma is among the diseases for which the IU Precision Health Initiative is focused on improving treatments, finding cures and developing preventions.
Remembering Tony Frimpong
Last week IU School of Medicine leaders shared information about funeral services for fourth-year medical student Tony Frimpong, who passed away on December 16 while traveling out of state. Services are scheduled this weekend in Massachusetts.
In a January 3 update memo to school colleagues, Bradley Allen, MD, PhD, senior associate dean for medical school education, and Regina Kreisle, MD, PhD, associate dean and director of IU School of Medicine-West Lafayette, wrote: “This is an incredibly difficult time for our school, the West Lafayette campus where Tony completed his first two years of medical school, and most especially for Tony’s classmates.”
The IU School of Medicine community expresses its condolences to the Frimpong family and Tony’s classmates and friends.
The Department of Mental Health Services at IU School of Medicine is available to provide mental health and personal counseling services to all students, residents and fellows. Faculty or staff who need assistance or information about individual and/or group support related to this loss should contact their employee assistance program:
- The IU Employee Assistance Program is available at 888-234-8327.
- The IU Health Employee Assistance Program may be reached at 800-745-4838, ext. 2. Provider well-being tools may also be accessed on the IU Health Team Portal.
Pediatric radiologist cultivates his Indiana roots with cider making
Leaning into his homemade cider press, Brandon Brown, MD, uses the full weight of his body to crush the apple juice into the basin below. What might seem like a scene out of an agrarian tale is an annual team-building event for Brown and his IU School of Medicine Department of Radiology colleagues. A pediatric radiologist and assistant professor of radiology and imaging sciences, Brown has planted more than 100 apple trees in the past 10 years. For the native Hoosier, making cider isn’t just a way to enjoy a homemade Indiana staple; it’s also a way to connect with his community and the local environment.
“I’ve always felt a little bit of loyalty to a sense of place,” Brown said. “I feel a commitment to our state and to our community here at IU School of Medicine. I really like the idea that we have a team of people who are committed to ensuring our community has the very best care. Caring for a local orchard and making cider with my colleagues is a great way to build that commitment to community and place.”
Learn more about Brown in this Faculty News blog post, including his views on work-life balance and how as a member of the school’s Teacher Learner Advocacy Committee he works to cultivate a culture of wellness. Also check out the first episode of his podcast series, MedStories, which focuses on “the good that happens every day” at IU School of Medicine.
Commencement to be held on Friday instead of Saturday this year
The beginning of 2019 means that commencement is right around the corner. As a reminder, the IU School of Medicine commencement ceremony will take place at 2 pm, Friday, May 10. The move from Saturday morning to Friday afternoon is being made to avoid time conflicts resulting from a change in IUPUI’s commencement. Besides moving the ceremony to Friday, there will be no major changes to IU School of Medicine’s commencement format or program. For more, read these details about the 2019 ceremony.
January 18 is last day to submit Trustees Teaching Award nominations
Each year the Indiana University Board of Trustees recognizes excellence in teaching through the prestigious Trustees Teaching Award. More than 50 IU School of Medicine teachers are expected to receive the award this year. Nominations for the 2019 awards are due Friday, January 18.
December 2018 research awards total nearly $2.9 million
Investigator Sponsor Type Project Title Begin Date End Date Awarded Dollars Liana G Apostolova National Institute On Aging New Testing the Dysconnection Hypothesis: Novel Connectomics Approaches for Early Detection and Progression of Alzheimer's Disease 12/1/2018 11/30/2019 $60,838 Ankit A Desai National Heart, Lung And Blood Institute New Pathogenic Role of IL-18 in Sickle Cell Cardiomyopathy and Inducible Ventricular Tachycardia 12/1/2018 3/31/2019 $423,124 Carmella Evans-Molina University Of Florida New Integrated Program for Human Pancreas Procurement and Analysis 10/1/2018 6/30/2019 $7,341 Brandon Michael Fritz National Institute On Alcohol Abuse And Alcoholism New Dorsal Striatal Adenosine A1 Receptors in Alcohol-Induced Synaptic and Behavioral Plasticity 9/26/2018 9/25/2019 $61,738 Rajani Mary George American Heart Association Incorporated New Epigenetic Regulation of Hand1 During Heart Development 1/1/2019 12/31/2020 $106,532 Lei Han American Heart Association Incorporated New A novel human lncRNA controls early mesoderm specification 1/1/2019 12/31/2020 $114,368 Irene Heredero Bermejo American Heart Association Incorporated New Characterization of TgDrpC, an atypical dynamin related protein in Toxoplasma gondii 1/1/2019 12/31/2019 $52,216 Jeffrey Allen Kline Society For Academic Emergency Medicine New The incidence of diagnosing cancer in the emergency department 7/1/2019 6/30/2020 $5,000 Charly Lai University Of Pittsburgh New A Phase II Trial for Metformin for Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction 7/1/2018 2/28/2019 $26,956 Troy A Markel Koret Foundation New Koret Foundation Research Support Funds 11/27/2018 11/27/2019 $50,000 Kieren J Mather Baylor College Of Medicine New Center for Identification and Study of Individuals with Atypical Diabetes Mellitus (Planning Grant) 9/10/2018 5/31/2019 $29,977 Raghu G Mirmira Riley Children's Foundation New Luke Bracken Wiese Fund for Juvenile Diabetes Research Grant 9/1/2018 8/31/2019 $100,000 Harikrishna Nakshatri University Of Notre Dame New Mechanisms of targeting triple negative breast cancer genomic vulnerability 9/1/2018 8/31/2019 $52,197 Sandra Katharina Prucka Michigan Public Health Institute New Midwest Genetics Network 10/1/2018 5/31/2019 $5,000 Katia Rothhaar Seattle Children's Research Institute Renewal (not prev committed) Saline Hypertonic in Preschoolers (SHIP) 11/1/2018 10/31/2019 $15,919 Dhritiman Samanta American Heart Association Incorporated New Elucidating the mechanisms behind Coxiella burnetii regulation of vesicular pH 1/1/2019 12/31/2020 $110,456 Don B Sanders Cystic Fibrosis Foundation New Standardizing Treatment of Pulmonary Exacerbations in Pediatrics (STOP-PEDS) 10/1/2018 9/30/2019 $213,625 Amy Yoshiko Sato American Society For Bone And Mineral Research New Training in novel techniques to evaluate muscle fiber composition and metabolism 11/1/2018 10/31/2019 $7,500 Titus K Schleyer Indiana University Health New Development of the Indiana Learning Health Systems Initiative 3/1/2018 2/28/2020 $299,987 Emily K Sims National Institute Of Diabetes, Digestive & Kidney New Defining the Generation and Cargo of Extracellular Vesicles During the Evolution of Type 1 Diabetes 12/5/2018 11/30/2019 $118,125 Dimitrios Stefanidis Indiana University Health Renewal (not prev committed) Advances in Medicine (AIM) Fostering Skill Building for Surgeons Project Period 2 1/1/2017 6/30/2018 $200,000 Method Tuuli Washington University New Optimizing management of the second stage of labor: multicenter randomized trial 8/1/2018 12/31/2018 $28,235 Cong Yan National Cancer Institute New Metabolic Regulation of PD-L1 in CD11c+ Cells 12/4/2018 11/30/2019 $547,418 Teresa Audrey Zimmers National Institute Arthritis Musculoskeletal Skin New Morbidity, Mortality and Mechanisms of Persistent uscle Wasting due to Abdominal Aortic Aneurysm-AAA Cachexia 12/15/2018 11/30/2019 $207,900
Impact of government shutdown on research agencies: What you need to know
Many federal research agencies are impacted by the partial federal government shutdown. During the shutdown, no new grants or contracts will be awarded by the impacted agencies. Grants.Gov, FastLane and Research.gov proposal preparation and submission will be available, but proposals will not be processed until the impacted agencies are reopened.
Unless otherwise notified by a federal agency or pass-through sponsor, performance on existing federally funded grants and contracts may continue during the shutdown.
- National Science Foundation
- National Aeronautics and Space Administration
- National Endowment for the Arts
- National Endowment for the Humanities
Several agencies already have their budgets in place and are not affected by the partial shutdown. These agencies include the Department of Education, the Department of Energy, the Department of Defense, and the Department of Health and Human Services, which includes the National Institutes of Health.
The IU Office of Federal Relations in Washington, DC, is closely monitoring the situation and will provide additional information as it becomes available. For information on specific agencies or programs, contact IU Federal Research Relations Director Laura Kolton at 202-816-3325 or firstname.lastname@example.org.
Hoosier volunteers needed for study to find new treatments for bone, muscle disorders
Researchers at IU School of Medicine's Indiana Center for Musculoskeletal Health are seeking volunteers of all ages and health conditions to participate in research to advance understanding of bone and muscle disorders, a leading cause of disability in the United States. While more than 1,000 participants have already been recruited, a total of 5,000 volunteers are needed.
It takes about an hour to participate in the study, which includes performing physical tests, providing a blood sample and undergoing bone mineral density scans--known as DEXA scans--to determine body composition and bone health. The physical tests include walking for six minutes and having walking speed, balance and grip strength measured.
The blood samples are stored within the Indiana Biobank. They are connected to the results of the physical performance tests and scans, as well as the volunteer's electronic medical record, to create a database. That database will be a treasure trove for researchers seeking to develop new treatments and cures for bone and muscle disorders.
Regenstrief Institute-MDClone partnership to accelerate data-driven medical research
Health care generates vast amounts of data that have the potential to drive medical research and improve health, but unlocking the power of those data for the greater good is often slow and challenging. To address this, Regenstrief Institute and MDClone of Israel have formed a partnership that aims to speed access to data for medical research, while ensuring patient privacy.
“Regenstrief is already the data steward and broker for one of the largest sets of biomedical data used in research around the region and the globe,” said Peter Embi, MD, Regenstrief Institute president and chief executive officer. “This partnership will enhance Regenstrief’s efforts to accelerate research and innovation by significantly shortening the time to deliver research-ready, privacy-preserving synthetic data, thereby enabling new discoveries, improving quality and reducing costs.”
“Having been in the health care IT world for more than two decades, I’ve seen the impact of Regenstrief’s many groundbreaking contributions to the field,” said Ziv Ofek, MDClone’s founder and chief executive officer. “I am privileged to begin working with Regenstrief, implementing MDClone’s innovative platform powered by our synthetic data engine that will fundamentally transform the use of data for improving health care throughout Indiana and beyond.”
Faculty and Staff News
Faculty, lecturers and lab mentors needed for summer oncology research program
Laboratory mentors, lecturers and clinical faculty are invited to participate in a summer translational oncology program jointly administered by Indiana University School of Medicine, Johns Hopkins University School of Medicine and Ohio State University College of Medicine.
Now in its fourth year at IU School of Medicine, the unique program, “Cancer in the Under-Privileged Indigent or Disadvantaged (CUPID),” will be held May 28-August 2. Opportunities include hosting a student in an Indianapolis campus lab, giving a lecture (on general oncologic principles and practices, specific diseases prevalent in underserved populations or health care disparities) or providing a shadow experience in the clinic.
Faculty mentors hosting a summer student in their laboratories will receive $1,000 to help cover lab-related expenses. Mentors are particularly needed who can provide hands-on research experiences for students to generate their own data at the lab bench. More information is available. To volunteer or with questions, contact Joe Dynlacht, PhD, at email@example.com, Jordan Holmes, MD, at firstname.lastname@example.org or Richard Zellars, MD, at email@example.com.
Start the new year by enrolling in medical library classes
Check out the courses offered by the Ruth Lilly Medical Library. Classes are open to faculty, staff and students. The January schedule includes these offerings:
Determining Your Research Impact
Tuesday, January 15; noon-1 pm
This class provides information on various metrics such as impact factors, Eigenfactors, the Becker Model and H-Indices. Attendees receive hands-on experience with using library resources to discover more information about tracking impact.
Wednesday, January 16; 3:30-4:30 pm
Tuesday, January 29; noon-1 pm
EndNote is a citation management software program allowing users to import citations from numerous literature databases into one spot. Users can then edit citations, add notes, import full text documents and use the program to format citations for articles, papers, grant proposals, etc.
Tech Talks: Introduction to Emerging Technologies in Medicine
Tuesday, January 29; noon-1pm
Class dates and registration are available. All classes can be streamed live via Zoom.
Plan to attend upcoming Culture & Conversation events
Culture & Conversation is a monthly discussion series about diversity-related issues, including representational diversity, inclusive working and learning environments and cultural competence. The spring schedule of events includes:
Wednesday, February 13: noon-1 pm
Maternal Mortality and Women’s Health
Tuesday, March 19: noon-1 pm
Abilities, Rights and Access to Health Care
Thursday, April 11: noon-1 pm
Click on the course titles for more details and to register.
Healthy Indiana Plan dialogue series begins January 24
“HIP: Health Equity, Responsibility and Community” is a six-part series exploring how the Healthy Indiana Plan (HIP) serves members and the state. The first session, featuring HIP Director Natalie Angel, will be held on Thursday, January 24, from 5-6:30 pm at the Shepherd Community Center in Indianapolis. Special note: Krista Brucker, MD, IU School of Medicine assistant professor of emergency medicine, will be the featured speaker at the March 21 event, “Opioids and Access.”
HPV webinar series kicks off January 22
IU School of Medicine National Center of Excellence in Women’s Health is co-sponsoring a human papilloma virus (HPV) series, Us vs. HPV, beginning Tuesday, January 22, coinciding with HPV Prevention Week. “Topics of the day” include:
- HPV vaccine update
- HPV and cervical cancer
- HPV-related non-gynecological diseases and cancers
- Cervical cancer: past, present and future
- HPV and cervical cancer champions
New IU Health chief diversity and inclusion officer named
Lisa Gutierrez has been named chief diversity and inclusion officer for Indiana University Health. Gutierrez has more than 20 years of experience in the field and most recently served as the diversity officer for Cardinal Health. She has a bachelor of science degree in marketing and organizational management from University of Colorado at Boulder.
Bien is new chief medical officer for IU Health West Central Region
James Bien, MD, has been appointed chief medical officer and vice president of quality and safety for IU Health Arnett and the health system’s west central region. Bien will serve as the senior executive for the 300-member IU Health Arnett Physician Group and oversee quality and patient safety.
Adjunct assistant clinical professor of pediatrics at IU School of Medicine, Bien earned his medical degree at Northwestern University and completed residency training at Cincinnati Children’s Hospital Medical Center.