Top News

  • Fresh perspectives on medical education: Education Day is tomorrow

    On Friday, March 6, IU School of Medicine will host its inaugural Education Day, with the theme, “Bringing Fresh Perspectives to Medical Education.” The event will be held from 8 am-4 pm in Hine Hall on the IUPUI campus.

    Education Day offers the opportunity for faculty, staff, residents, fellows and students (professional, graduate and undergraduate) from all departments and campuses to showcase their medical education research through oral presentations, small group discussions and poster sessions. Keynote speaker is Susan E. Skochelak, MD, MPH, chief academic officer, group vice president, Medical Education, American Medical Association. Skochelak’s presentation is titled “Medical Education Innovation: Roadmap for the Next Decade.” Plenary speaker is Michael A. Barone, MD, MPH, vice president, Licensure Programs, National Board of Medical Examiners, who will present “USMLE Numeric Scoring: A 360 Assessment.”

    Email Komal Kochhar at kkochhar@iupui.edu with questions.

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  • Spring All School Meeting and Shekhar reception scheduled for April 29

    IU School of Medicine Dean Jay Hess, MD, PhD, MHSA, and the Faculty Steering Committee invite faculty, staff and learners to attend the spring All School Meeting from 4:30-6 pm, Wednesday, April 29, in Walther Hall (R3), C203. Hess will provide critical updates, and there will be opportunities to ask questions.

    While in-person attendance is encouraged, the meeting will be available via live webstream. Instructions for participating remotely will be posted on the Faculty Steering Committee webpage

    A reception to celebrate Executive Associate Dean for Research Affairs Anantha Shekhar, MD, PhD, who will be leaving IU School of Medicine in May, will be held immediately following the meeting in the third floor atrium of Walther Hall. Shekhar will be honored for his 30-plus years of service to IU and the state of Indiana. As a nationally recognized researcher and leader of IU School of Medicine’s research enterprise, Shekhar leaves an indelible imprint on the school community, including those he has taught, those he has worked alongside and those whose lives have been impacted by his research.

    Spring All School Meeting
    Wednesday, April 29
    4:30-6 pm
    Walther Hall (R3), C203
    Available via live web stream (details will be posted on the Faculty Steering Committee webpage)

    Celebrating Anantha Shekhar, MD, PhD
    Wednesday, April 29
    6-7:30 pm
    Walther Hall (R3), third floor atrium
    Refreshments will be served. 

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  • Regional campus spotlight: IU School of Medicine–Evansville

    What makes IU School of Medicine–Evansville unique? Students say it’s the close-knit campus community and the new Stone Family Center for Health Sciences, a state-of-the-art facility dedicated to collaborative medical education and clinical research.

    “There’s more to Evansville than meets the eye,” says one student. Find out more about this extraordinary regional campus—and why IU School of Medicine students enjoy studying there—in this highlight video.

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Research News

  • February research awards and grants total over $4 million

    Investigator Sponsor Type Project Title Begin Date End Date Awarded Dollars
    Alan Breier Eskenazi Health Renewal (not prev committed) Prevention and Recovery Center for Early Psychosis (PARC) and Coordinated Specialty Care (CSC) Network (YR4) 9/1/2019 8/31/2020 $225,369
    Jennifer L Carnahan National Institute On Aging New The Coming Home After Rehabilitation and Transition from a Skilled nursing facility with Dementia Study (The CHARTS-D Study) 2/1/2020 1/31/2021 $183,417
    Yen-Shan Chen Diabetes Research Connection New Device-Driven Protein Engineering with Application to Insulin and Glucagon 1/1/2020 12/31/2020 $75,000
    Linda A DiMeglio University Of South Florida Renewal (not prev committed) Data Coordinating Center for Type 1 Diabetes TrialNet (UC4) 1/1/2020 1/31/2020 $29,527
    Jonathan Nicholas Flak American Diabetes Association New Targeting the VMN to Understand Hypoglycemia Pathogenesis 9/1/2019 12/31/2019 $29,057
    Tatiana M Foroud Foundation For Peripheral Neuropathy Renewal (not prev committed) Peripheral Neuropathy Research Registry 1/1/2020 12/31/2020 $59,207
    Tatiana M Foroud Mayo Clinic, Rochester New ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) - Clinical Core 9/15/2019 6/30/2020 $1,089,818
    Heather Francis National Institute Of Diabetes, Digestive & Kidney New Mechanisms of mast cell/cholangiocyte regulation of non-alcoholic fatty liver disease progression 8/1/2019 5/31/2020 $352,910
    Kara Garcia Washington University New Analysis of Surface Growth from Magnetic Resonance Imaging of the Developing Brain 10/1/2018 9/30/2019 $10,357
    Millie M Georgiadis Foundation For Applied Molecular Evolution, Inc New Darwinism from Artificial Genomes 12/15/2019 11/30/2023 $584,919
    Timra D Gilson Cure Sma New ¿COP complex dependent axonal transport of RNA 3/1/2020 2/28/2022 $150,000
    Al Hassanein American Association Of Plastic Surgeons New Tissue Nanotransfection Induced Lymphovenous Shunt in Murine Lymphedema Model 7/1/2020 6/30/2022 $30,000
    Woody Hopf National Institute On Alcohol Abuse And Alcoholism New Insula Circuitry and Compulsive Alcohol Drinking 12/18/2019 5/31/2020 $225,045
    Myda Khalid Nationwide Children's Hospital New CUREGN 2.0 - Midwest Pediatric Nephrology Consortium - PCC 8/16/2019 5/31/2020 $21,392
    Karl Russell Koehler National Institute On Deafness And Other Comm. Dis New Modeling Neurofibromatosis Type 2 with Inner Ear Organoids 1/31/2020 1/30/2021 $37,163
    Yunlong Liu University Of Utah New Schistosoma Mansoni Infection During Pregnancy: Dissecting the Implications to Fetal Immunity 10/1/2019 1/31/2020 $23,803
    Larry Wayne Markham Vanderbilt University Medical Center New Development of a Multimodal Biomarker Platform for Predictive Risk Stratification of Cardiac Disease in Duchenne Muscular Dystrophy 9/15/2019 8/31/2020 $76,769
    Eric Thomas Meininger Tawani Foundation New School wellbeing in gender diverse children and adolescents 1/1/2020 12/31/2022 $143,250
    Raghu G Mirmira Riley Children's Foundation Renewal (not prev committed) Madison Anderson Cardiology Research Endowment 7/1/2019 6/30/2020 $14,456
    Dawn M Neumann Rehabilitation Hospital Of Indiana New Resource Facilitation: A promising initiative shown to decrease recidivism in exiting offenders with traumatic brain injury 1/1/2020 12/31/2024 $110,568
    Kwangsik Nho Duke University New Metabolic Signatures Underlying Vascular Risk Factors for Alzheimer-type Dementias 1/1/2020 5/31/2020 $100,000
    Hongxia Ren National Institute Of Diabetes, Digestive & Kidney New Metabolic Function of Gpr17 in Gastrointestinal Tract 1/1/2020 12/31/2020 $401,224
    Steven J. Steiner Cincinnati Children's Hospital Medical Center New Coproducing Learning Health System Culture and Processes to Accelerate Patient Centered Outcomes Research in the ImproveCareNow Network 5/1/2019 9/30/2020 $20,000
    Brian Walker Oregon Health & Science University New SWOG Network Group Operations Center of the NCTN 11/1/2019 2/29/2020 $4,779
    Fletcher A White University Of California, San Diego New Toll-like receptor 4 signaling in chronic neuropathic pain after SCI 12/31/2019 12/30/2020 $4,950
    Xiao-Ming Xu Purdue University New A novel enzymatic mechanism for removing neurotoxic aldehydes after rodent spinal cord injury 9/15/2019 8/31/2020 $52,934

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  • Focus on lab optimization: Researchers embrace transition from paper to electronic lab notebooks

    Editor’s note: IU School of Medicine shares recommendations and resources to help researchers optimize their labs as part of a schoolwide plan. This article is part of a series about how researchers can use new tools and best practices to improve data quality and management, reduce risk, increase efficiency, and address health and safety issues in their labs.

    The IU School of Medicine Office of Research Affairs announced the availability of an electronic lab notebook system early last year to enhance collaboration and provide a digital alternative to paper notebooks in research labs. The electronic lab notebook licensed by IU School of Medicine, known as LabArchives, is available at no charge to students, faculty and staff at IU School of Medicine.

    Erin Foster, MLS, is the Data Services librarian at IU School of Medicine. She says the availability of LabArchives gives labs an opportunity to streamline their data management practices. Use of an electronic lab notebook can also encourage better communication among lab members.

    Prior to LabArchives, IU School of Medicine did not offer an approved electronic lab notebook system for use. Foster said IU School of Medicine’s commitment to the project has helped with adoption.

    “The principal investigators who volunteered as early adopters were invaluable to the success of this initiative. It’s been a really nice group effort,” she explained. “We started with 136 LabArchives users in April 2019 and now we have nearly 350 users at IU School of Medicine.”

    Carmel Egan, PhD, associate dean of research affairs, also expressed enthusiasm about the transition from paper to electronic lab notebooks.

    “LabArchives at IU School of Medicine has given us another opportunity to enhance research efficiency here at the school,” Egan said. “It’s a significant improvement, and it allows the talented lab researchers to readily document lab results and optimize rigor in documentation overall.”

    LabArchives is also available to faculty, staff and students on Indiana University’s Bloomington campus. All researchers are encouraged to take advantage of this free resource.

    Learn more about LabArchives at IU.

     

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  • Boosting recovery: Scientists study link between energy levels, spinal cord injury

    Each year, thousands of people in the United States experience a spinal cord injury, damaging the system of nerves that the brain and body use to communicate.

    A team of researchers from IU School of Medicine, in collaboration with the National Institute of Neurological Disorders and Stroke, have investigated how boosting energy levels within damaged nerve fibers or axons may represent a novel therapeutic direction for axonal regeneration and functional recovery.

    The study, published March 3 in “Cell Metabolism,” examined three central nervous system injury mouse models to determine how energy levels affect spinal cord injury repair.

    Investigators from the Spinal Cord and Brain Injury Research Group at Stark Neurosciences Research Institute—led by Xiao-Ming Xu, PhD—and a team led by Zu-Hang Sheng, PhD, at Porter Neuroscience Research Center at the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, collaborated on the research.

    “Spinal cord injury is devastating, affecting patients, their families and our society,” Xu said. “Although tremendous progress has been made in our scientific community, no effective treatments are available for patients with such disorders. There is definitely an urgent need for the development of new strategies for patients with spinal cord injury.”

    Visit the Newsroom for more on the research.

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  • Zimmers named co-program leader of TMM at cancer center

    Teresa Zimmers, PhD, has been named co-program leader of Tumor Microenvironment and Metastasis (TMM) at the IU Simon Comprehensive Cancer Center. She joins Ken Nephew, PhD, and Theresa Guise, MD, as co-leader.

    The Zimmers lab studies the progressive weight loss that afflicts most patients with advanced cancer, including 85 percent of patients with pancreatic cancer. This wasting syndrome, cachexia, is thought to cause about 25 percent of cancer deaths. Her lab seeks novel therapeutics to slow cachexia in order to preserve cardiac and skeletal muscle, and improve quality and length of life.

    Zimmers is the H.H. Gregg Professor of Cancer Research, professor of surgery, adjunct professor of biochemistry and molecular biology, and adjunct professor of otolaryngology-head and neck surgery at IU School of Medicine. Since 2018, she has been co-leader of the cancer center’s Pancreatic Cancer Working Group.

    For more, visit News Briefs.

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Faculty and Staff News

  • IU updates COVID-19 guidelines

    While there are currently no known cases of COVID-19 (coronavirus) in Indiana or at Indiana University, IU is closely monitoring the rapidly changing situation and is actively working to plan and prepare for a potential outbreak, which includes coordination with partners across the university and local and state health departments and hospitals.

    As of Wednesday, March 4, IU has restricted travel to the following countries:

    • China
    • Iran
    • Italy
    • South Korea

    Anyone traveling to a country with a Centers for Disease Control level 2 or 3 travel alert will be required to self-quarantine off campus for a period of 14 days before returning to IU campuses. Currently, those countries include China, Iran, Italy, Japan and South Korea. Questions about travel should be emailed to AVPpsia@iu.edu.

    Visit coronavirus.iu.edu and read the university’s March 4 Public Safety Advisory for current details.

    In addition, IU Health continues to monitor the status of COVID-19 with the Indiana State Department of Health and the CDC. IU School of Medicine faculty and staff with access to the IU Health team portal will find tips and resources for IU Health team members. 

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Opportunities

  • NIH offering shared instrumentation grants

    The National Institutes of Health offers several programs that encourage applications from groups of NIH-supported investigators to buy or upgrade specialized, commercially available instruments or integrated systems. View the links below for specific details, application details and deadlines.

    Shared Instrumentation Grant (SIG) Program
    High-End Instrumentation Grant (HEI) Program
    Shared Instrumentation for Animal Research (SIFAR)

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  • Save the date: April 8 event to explore gender, salary and the art of negotiation

    The true art of negotiating like a pro is to get what you want. Unfortunately, survey research reveals that when compared to men, a good number of women are less successful at negotiating. Women often struggle with finding the right balance—strengthening relationships without sacrificing the bottom line. On Wednesday, April 8, plan to attend “Negotiating the Divide: Gender and Salary” to learn: 

    • Innovative and successful strategies to get what you want and what you deserve—the new job, promotion or successful business deal—out of negotiation
    • Ways to adopt a powerful mindset
    • How to eliminate the most common negotiation mistakes made by women

    More details and registration are available.

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  • Supporting cancer survivors: Karuna Precision Wellness Center open house is March 12

    In Sanskrit, Karuna is the practice of being present to another who is suffering and acting out of compassion to assist them. The Karuna Precision Wellness Center, the first center of its kind in Indiana to address the needs of cancer survivors, aims to optimize long-term health and wellness through precision wellness plans that integrate physical functioning and fitness, mental and cognitive health services, and nutrition.

    Learn more at the center’s open house on Thursday, March 12, at 5:30 pm. The center is located at The Healthplex, 3660 Guion Road, Suite 325, in Indianapolis. The Karuna center is supported by IU School of Medicine, the IU Precision Health Initiative and Indiana CTSI. More details are available.

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  • Deadline is April 1 to apply for cancer center Wright scholarship

    Faculty reminder for students: The IU Simon Comprehensive Cancer Center William J. Wright Scholarship Fund rewards second- and third-year medical students conducting cancer research and who wish to pursue a career in the care of patients with cancer. Selection criteria also include students who have displayed strong humanistic qualities throughout their medical school career.

    The expectation for this award is that the student will devote at least two months of their school year to a project that will further the care of patients with cancer, including a formal basic, translational or clinical science research project, quality improvement project, health outcomes research, or cancer awareness program. Students need to identify a mentor and a research project, which should be included in the application. Awardees must attend Cancer Research Day on Thursday, May 7, 2020.

    Application deadline is Wednesday, April 1, and details are available. Note: Students with research grants that already support their education are not eligible.

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Partner News

  • Gottlieb to retire from IU Health leadership post next month

    Jonathan E. Gottlieb, MD, will retire April 30 from his position as executive vice president and chief medical officer for IU Health. Gottlieb has substantially evolved IU Health’s quality, safety and clinical effectiveness capabilities. He built a new clinical leadership team and partnered with IU School of Medicine to ensure that IU Health’s clinical, research and educational activities are of the highest caliber.  

    A national executive search will be conducted for Gottlieb’s successor.

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  • IU Health Foundation receives $1 million from Irsay to fund addiction services

     Indianapolis Colts owner and CEO Jim Irsay is pledging $1 million to the IU Health Foundation to be used by IU Health to increase access to addiction services for people in need across Indiana.

    “Addiction is terribly difficult for everyone involved, and it’s important that people aren’t shamed by this disease, because shame kills,” Irsay said. “IU Health has a tremendous program, and we are committed to partnering with them to address this problem across Indiana.”

    For more on Irsay’s gift, visit iuhealth.org.

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Around Campus

  • IU School of Medicine–South Bend hosts annual Mini Medical School

    IU School of Medicine–South Bend will welcome area physicians and public health advocates in March and April for the 24th annual Mini Medical School Lecture Series. Topics include the latest on CBD oil, advances in heart surgery and cancer research in Indiana. Lectures begin on Wednesday, March 11, and continue for five consecutive Wednesdays. All events will be held in the 1st Source Bank Auditorium, Raclin Carmichael Hall.   

    2020 Mini Medical School Lecture Series
    All lectures begin at 7 pm.
    March 11: Carlton Lyons, MD
    March 18: James Flynn, MD
    March 25: Troy Weirick, MD
    April 1: Mark Fox, MD, Heidi Beidinger-Burnett, PhD, MPH, and Kathy Schuth
    April 8: Patrick Loehrer, MD

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