Top News

  • ICYMI: Direct from the Dean and All School Meeting recording

    In an email to the IU School of Medicine community on Friday, May 1, Dean Jay L. Hess, MD, PhD, MHSA, provided a recap of the spring All School Meeting, which was held on Wednesday, April 29.

    An excerpt from Hess’s message:

    “It’s difficult to give an update on the school without first talking about COVID-19. The impact it has had on our school, our community and our world has been immense. Though we don’t know what lies ahead, the pandemic has already become the biggest challenge that we will face in our careers. 

    That’s a challenge I’m proud to say we’ve met—from our physicians fighting the virus on the frontlines, to our faculty keeping curriculum and policies for our learners and residents on track, and our support staff adjusting to a host of changes with nimbleness and understanding. While the footprint of COVID-19 on this year will be large, we have much to celebrate—both in our accomplishments before the pandemic hit, and the promising future we have ahead.”

    Read more in this Direct from the Dean blog post and access a recording of the All School Meeting.

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  • Shekhar receives IU President’s Medal

    Anantha Shekhar, MD, PhD, associate vice president for university clinical affairs and research and executive dean for research affairs at the IU School of Medicine, has been awarded the IU President's Medal for Excellence.

    The medal is the highest honor the university's president can bestow. It recognizes those who've made outstanding professional achievements and provided exceptional service to the university.

    IU President Michael A. McRobbie surprised Shekhar with the award during the IU School of Medicine spring All School Meeting on Wednesday, April 29.

    "In gratitude for your extraordinary leadership at IU and the enormous contributions you have made to translational science and the search for cures and treatments for diseases and disorders, I am privileged and honored to present you with the President's Medal for Excellence," McRobbie said.

    For more on Shekhar’s award, visit News at IU.

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  • Virtual commencement is next Friday

    IU School of Medicine will honor the Class of 2020 with a virtual commencement and graduate recognition ceremony at 10 am, Friday, May 15. The Surgeon General of the United States, Jerome M. Adams, MD, MPH, will give the keynote address. Adams, the nation’s public health authority and a leader in the response to the COVID-19 pandemic, is a graduate of IU School of Medicine and a former faculty member.

    The graduate recognition ceremony will be live streamed, and all are welcome to attend. Live stream access details will be provided in next week’s issue of INScope.

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  • MD students and faculty members partner in COVID-19 course

    As frontline physicians and health care workers have had to quickly learn about best practices in treating COVID-19 and keeping hospitals safe, Medical Student Education leaders at IU School of Medicine also have had to adjust how they’re training the next generation of doctors.

    Pulling third- and fourth-year medical students out of clinical rotations in mid-March meant leaders were faced with a fast turnaround on revamping spring curriculum. Bradley Allen, MD, PhD, senior associate dean for medical student education, said the MD program needed new virtual courses to fill in the gap of rotations while still giving students an opportunity to build upon their skills.

    At the top of the list for the program is a virtual COVID-19 course required for all IU School of Medicine third- and fourth-year learners—encompassing more than 700 students across all nine campuses.

    Allen and Paul Ko, MD, associate dean for curricular development and oversight, said the course will likely be the largest in the United States. Few medical schools have implemented COVID-19-related coursework, but most universities offer it as an elective, they said.

    The Association of American Medical Colleges also invited Allen and Ko to share their experiences in creating the course during a national webinar for medical schools. IU School of Medicine will join Harvard Medical School on the webinar to discuss their two courses.

    The two-week course, which began on Wednesday, April 29, is divided into 15 different modules focusing on subjects, such as the science behind the disease, public policies, communication and social media, evidence-based medicine and leadership. Unlike with most MD courses, it was the students that helped develop the course curriculum, with the review and guidance of faculty.

    Learn more about the course, including students’ perspectives, in this Student Life blog post.

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  • Urologists use technology to keep educating during pandemic and beyond

    As the COVID-19 pandemic leads to major changes for people around the world, members of the IU School of Medicine Department of Urology are using new technology to continue educating their residents. And they plan to keep using the new method of lecturing after the pandemic is over to benefit even more health care professionals.

    “This is going to be a great resource for residents, practicing urologists, referring physicians and more,” said Chandru Sundaram, MD, IU School of Medicine Department of Urology residency director.

    When the coronavirus spread through the United States forced people to practice social distancing and stay home as much as possible, many departments within IU School of Medicine had to change planned events to be held virtually. For the urology department, previously scheduled lectures and presentations for residents had to shift to virtual methods as well.

    Now, the department is embracing the change and opening up these interactive lectures to other practicing urologists, referring physicians, students and more.

    “We are planning different types of interactive sessions. The first is the “Virtual Operating Room” with videos illustrating the steps of surgeries, followed by a discussion on managing difficult anatomical situations as well as managing intra-operative problems and complications,” Sundaram said. “The second group of talks is case-based, where interesting cases that illustrate management issues will be discussed. There will also be talks on reviews and updates on topics of interest.”

    The presentations are currently being held at least twice a week. The department also plans to continue these online lectures long-term, even after the pandemic is considered over.

    For more, including details on how to access upcoming and past lectures, check out this Spirit of Medicine blog post.

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Research News

  • April research awards total over $14 million

    Investigator Sponsor Type Project Title Begin Date End Date Awarded Dollars
    Alka Khaitan National Institute Of Child Health, Human Devl. New Immune exhaustion in perinatal HIV infection 4/1/2020 3/31/2021 $315,859
    Andrew J Saykin Duke University New Alzheimer's Gut Microbiome Project (Project 1) 12/13/2019 8/31/2020 $42,971
    Andrew J Saykin Duke University New Alzheimer's Gut Microbiome Project (Core 1) 12/13/2019 8/31/2020 $71,667
    Andrew J Saykin Duke University New Alzheimer's Gut Microbiome Project (Admin Core) 12/13/2019 8/31/2020 $10,308
    Beatrice Mihaela Stefanescu Riley Children's Foundation New Riley Maternity and Newborn Health - Newborn Follow-up Operational Expenses 7/1/2019 6/30/2020 $162,172
    Brian Heath Mullis Aotrauma North America New Correspondence of Initial Metabolomic Response with Surgical Metabolomic Response in Patients Sustaining Severe Peri-articular Lower Extremity Fractures 2/24/2020 6/30/2021 $9,750
    Brian Pierchala National Institute On Deafness And Other Comm. Dis New Growth factors in the development and physiology of geniculate taste neurons 6/3/2019 5/31/2020 $457,952
    Brian Pierchala National Institute Neurological Disorders & Stroke Renewal (not prev committed) A p75/Ret receptor complex as an integrator of survival and death 5/1/2020 4/30/2021 $448,387
    Brian Walker Leukemia And Lymphoma Society New The impact of Non-Coding Somatic Mutations on the Prognosis and Progression of Multiple Myeloma 10/1/2019 6/30/2022 $524,938
    Carmella Evans-Molina Riley Children's Foundation New Richardson¿s Riley Children¿s Foundation Award 1/1/2020 12/31/2020 $25,000
    Clement L Ren University Of North Carolina At Chapel Hill New Assessing Effectiveness of CF Infection Prevention and Control Guidelines 9/1/2019 8/31/2020 $12,393
    Clement L Ren Cystic Fibrosis Foundation Renewal (not prev committed) Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT) Therapeutics Development Center2015 Policies and Guidelines Governing Renewal 4/1/2020 3/31/2021 $294,057
    Cynthia Diane Brown Cincinnati Children's Hospital Medical Center Renewal (not prev committed) A Cystic Fibrosis Collaborative Chronic Care Network Care Model of the Future: Proposal for Piloting a Learning Health System 1/1/2020 12/31/2020 $30,464
    David E Nelson National Institute Allergy & Infectious Diseases Renewal (not prev committed) Genetic analysis of mechanisms of chlamydial immune evasion 4/1/2020 3/31/2021 $589,700
    Dimitrios Stefanidis Indiana University Health Renewal (not prev committed) Advances in Medicine (AIM) Fostering Skill Building for Surgeons Project Period 4 7/1/2019 6/30/2021 $400,000
    Emily K Sims University Of Miami New The George S. Eisenbarth nPOD Award for Team Science 1/1/2020 12/31/2020 $33,000
    Eri Hashino National Institute On Deafness And Other Comm. Dis Renewal (not prev committed) Modeling Inner Ear Differentiation with Pluripotent Stem cells 5/1/2020 4/30/2021 $573,417
    Erik A Imel National Institute Arthritis Musculoskeletal Skin New Sarcopenia: computable phenotypes and clinical outcomes. 4/20/2020 3/31/2021 $235,788
    Frank Yang Steven & Alexandra Cohen Foundation New Development of therapeutic compounds against active and persistent Borrelia burgdorferi 6/1/2020 5/31/2024 $672,153
    Gustavo A Arrizabalaga National Institute Allergy & Infectious Diseases New Regulation of mitochondrial morphodynamics in Toxoplasma gondii 3/3/2020 2/28/2021 $392,803
    Harikrishna Nakshatri Susan G. Komen Breast Cancer Foundation New Harnessing genetic ancestry-dependent differences in normal breasts for biomarker discovery 2/25/2020 2/24/2021 $125,000
    J Dennis Fortenberry University Of Alabama Birmingham Renewal (not prev committed) Sexually Transmitted Infections Clinical Trials Group 9/15/2019 7/28/2020 $5,573
    James C. Williams National Institute Of Diabetes, Digestive & Kidney New Essential characterization of the Randall's plaque-overgrowth interface 5/1/2020 3/31/2021 $237,750
    James C. Williams University Of Washington New In-Office, Ultrasound-Based Breakage and Removal of Urinary stones 9/3/2019 6/30/2020 $448,005
    Jeffrey F Peipert Riley Children's Foundation Renewal (not prev committed) Center for Maternity and Newborn Health 7/1/2019 6/30/2020 $1,003,210
    John J Turchi National Cancer Institute New Discovery and development of Ku-targeted small molecule inhibitors: A novel mechanism of DNA-PK inhibition 3/13/2020 2/28/2021 $603,569
    Julie L Welch University Of Pittsburgh New Testing the Effectiveness of the Customized Career Development Platform (CCDP): A Cluster Randomized Trial 1/15/2020 12/31/2020 $9,313
    Kara Garcia Washington University New Analysis of Cortical Growth from MRI in Children Born Preterm 12/1/2019 11/30/2020 $15,139
    Karl D Shively Johns Hopkins University New A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring (EMS BinD Study) 2/7/2020 9/29/2021 $10,460
    Linda A DiMeglio University Of Minnesota New Hybrid Closed Loop Thearapy for Beta cell Preservation in New Onset Type I Diabetes: A Proof-of-Concept Study 9/1/2019 8/31/2020 $334,583
    Mark R. Kelley Purdue University New Big Data Training for Cancer Research 9/17/2019 8/31/2020 $19,308
    Martin Rhys Farlow University Of Southern California New TRC-PAD Program: In-Clinic Trial-Ready Cohort (TRC) 7/1/2019 4/30/2020 $608,475
    Method Tuuli University Of Texas At Austin New Optimizing management of the second stage of labor: multicenter randomized trial 8/1/2019 12/31/2020 $28,857
    Michael Holmes American Heart Association Incorporated New Translational control during bradyzoite formation in the heart pathogen Toxoplasma gondii 1/1/2020 12/31/2021 $139,336
    Raghu L Motaganahalli Purdue University New Intermittent pneumatic compression to improve the outcome of revascularization for critical limb ischemia 5/1/2019 12/31/2020 $26,810
    Ronald C. Wek National Institute Of General Medical Sciences New Regulation and Function of Integrated Stress Response 5/1/2020 4/30/2021 $386,355
    Sarah Elizabeth Wiehe National Institute Of Child Health, Human Devl. New Leveraging data to identify opportunities to address insecure care connections and poor health outcomes among people living with HIV 4/13/2020 2/28/2021 $787,410
    Seethal A Jacob Indiana State Department Of Health Renewal (not prev committed) Sickle Bright: Transitioning to a Bright Future-a Continuation 11/1/2019 6/30/2021 $247,168
    T George Hornby Rehabilitation Institute Of Chicago Renewal (not prev committed) Rehabilitation Research Training Center (PRIMER and VIVRANT) - Transfer (RHI Subaward) 9/30/2019 9/29/2020 $75,683
    Tatiana M Foroud Broad Institute New Schizophrenia Spectrum Biomarkers Consortium (SSBC) Study 1/1/2020 12/31/2020 $118,765
    Tatiana M Foroud Duke University New The Alzheimer's Gut Microbiome Project 12/13/2019 8/31/2020 $495,933
    Tatiana M Foroud Children's Tumor Foundation New Children's Tumor Foundation Biorepository 5/31/2019 5/30/2024 $250,000
    Timothy W Corson National Eye Institute New Short-Term Training in Ophthalmology Research for Medical Students 5/1/2020 4/30/2021 $48,092
    Uma Sankar National Institute Arthritis Musculoskeletal Skin New CaMKK2 Signaling in Osteoarthritis 3/13/2020 1/31/2021 $563,023
    William J. Sullivan National Institute Allergy & Infectious Diseases New GCN5a and cyst development in the AIDS-opportunistic pathogen Toxoplasma 1/21/2020 12/31/2020 $190,135
    X Charlie Dong National Institute Of Diabetes, Digestive & Kidney New Role of ATG14 in the regulation of hepatic function 6/1/2020 3/31/2021 $426,682
    Xinna Zhang Us Army Medical Research Acquisition Activity New Identification of Therapeutic Vulnerability in Prostate Cancer Harboring Chromosome 17p Loss 9/1/2020 8/31/2023 $1,188,750
    Yansheng Du National Institute On Aging New The Pathogenic Role of Pb in Cerebral Amyloid Angiopathy and AD 2/1/2020 11/30/2021 $251,595
    Yu-Chien Wu National Institute Neurological Disorders & Stroke New Comprehensive White-matter Microstructure-informed Analytical Methods to Elucidate Neurobiological Mechanisms of Sports-related Concussion (SRC) 4/15/2020 3/31/2021 $380,222
    Zhiyong Tan Us Army Medical Research Acquisition Activity New Targeting lysosomal transient receptor potential channel mucolipin-1 to treat neuropathic pain associated with diabetic peripheral neuropathy 3/1/2020 2/28/2022 $314,784

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  • PHI teams still moving forward despite pandemic delay

    Although the Precision Health Initiative (PHI) teams would prefer to be working as usual during this time, they are skillfully adjusting to the ever-changing conditions presented by the COVID-19 pandemic, while keeping an eye fixed toward future progress. Visit Precision Health for a roundup with team leaders in Alzheimer’s disease, multiple myeloma, pediatric sarcomas, triple negative breast cancer and Type 2 diabetes/gestational diabetes to see the research that’s still ongoing.

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  • School seeking blood donations from people recovered from COVID-19

    IU School of Medicine is asking all Indiana residents who have recovered from COVID-19 to donate blood for research designed to improve testing, develop treatments and better understand the resulting health complications from the disease. Blood samples will be stored at the Indiana Biobank, where donations will be deidentified, linked to health data and accessed by approved researchers for testing. While staff at the Indiana Biobank are encouraging volunteers and fielding calls for donations, IU School of Medicine Assistant Professor of Psychiatry Brandon Oberlin, PhD, is leading the call for volunteers after having contracted COVID-19 himself.

    Oberlin is a researcher whose work is focused on understanding the neurobiology of addiction-related decision-making. In spite of being cautious, he still became ill from the virus, even after his lab was closed—but before the state’s stay at home order was firmly in place. “I lost my sense of smell for five days and knew I had it,” said Oberlin. “My experience shows how highly contagious this disease is.”

    So as a scientist, when he heard about the Indiana Biobank’s efforts to collect blood from recovered COVID-19 patients, he knew he had to join the fight. “As a research scientist, I know how important data collection is; the more data we have, the more we will learn, and the answers will come more quickly,” said Oberlin. “Like myself, I want everyone in Indiana who was COVID-19 positive and has recovered, which is now over 10,000 Hoosiers, to donate blood.”

    According to the Indiana Biobank, any member of the recovered public in Indiana who wishes to donate blood will be considered “recovered” if they are either 28 days symptom free, past the first day he or she had no symptoms or, are symptom free and can provide a confirmatory negative test that was done via a nasal or oral swab.

    For more on donating for this cause, visit the Newsroom.

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Faculty and Staff News

  • Larry Cripe, MD, honored as physician mentor of the year

    Larry Cripe, MD, associate professor of medicine, has received the 2020 Physician Mentor of the Year Award. Serving as a physician mentor with the same cohort of mentees for the past four years, Cripe was described by one of his mentees as “someone who challenged us to find meaning in our thoughts, beliefs and actions. He helped us explore parts of ourselves that we often ignore. He reminded us that we are human before anything else. He encouraged us to remember why we chose this journey.”

    The Physician Mentor of the Year Award recognizes physician mentors who go above and beyond for their mentees.

    Read more about Cripe other faculty honored for mentoring this year in this MD Student News blog post. Details on the Physician Mentor Program are also available.

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  • Nominations for Leadership in Academic Medicine Program due June 5

    Faculty Affairs, Professional Development and Diversity is accepting nominations for the 2020-2021 Leadership in Academic Medicine Program (LAMP). LAMP is a cohort-based, yearlong faculty development and orientation program designed for faculty in the second or third year of their appointment.

    LAMP session dates:
    September 10, 2020
    October 15, 2020
    November 19, 2020
    December 17, 2020
    January 14, 2021
    March 11, 2021
    April 15, 2021
    May 13, 2021

    To be nominated, a brief statement of support is needed from your chair or division director no later than Friday, June 5. After the nomination, you must submit a one-page document describing your career goals, including what you want to accomplish in the next three years. Final application deadline is Friday, June 26.

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  • Share your COVID-19 stories

    If you have a unique story or photo of your COVID-19 experience or how teams are adapting and working together during this time, the Office of Strategic Communications wants to hear from you. Email photos or story details to Katie Duffey, interim director of strategic communications and visual media, at kaduffey@iu.edu.

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  • Long named emeritus professor

    Bruce W. Long, director of radiologic and imaging sciences and associate professor of radiologic and imaging sciences, has been approved for emeritus status. The new title was effective upon his April 1 retirement from IU School of Medicine.

    Long joined the school in 1985 as an assistant professor and was promoted to associate professor in 1991. He was appointed director of the radiologic and imaging sciences program in 2005 and served in that role until his retirement. The program thrived and expanded under Long’s leadership. In addition to the program directorship, Long taught numerous classes in the radiography program and gave more than 40 presentations at postgraduate and CME courses. He served as member, chair or president of more than 50 university-level committees, as well as several state committees. Long is the recipient of three grants and a number of teaching and research awards at the national level.

    Emeritus designation may be awarded upon retirement from IUPUI to faculty members and others as recognition of "substantial contributions to the university in the fields of teaching, research and/or service." Long’s emeritus status was approved by IUPUI Executive Vice Chancellor and Chief Academic Officer Kathy Johnson. IU School of Medicine congratulates Long and appreciates his contributions to the school and university.

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Opportunities

  • Global Health Scholars Day is online today

    The IU Center for Global Health convenes Global Health Scholars Day each May to showcase the excellent work being done by the IU community to improve the care of patients worldwide, research the complexities of global health, and educate learners about the care of local and global populations.

    Global Health Scholars Day features poster presentations, a photo contest and the opportunity for those interested in global health throughout the university to network and share information. This year’s Global Health Scholars Day will be held virtually via the IU Center for Global Health website with posters and photos now available for review and comment. Live presentations will begin at 5 pm, Thursday, May 7. ​

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  • Tomorrow on Zoom: Front-line emergency medicine physicians discuss COVID-19

    Plan to attend a panel discussion to hear from emergency medicine and critical care physicians who have experienced COVID-19 firsthand as they share the ups and downs and the trials along the way.
    Members of the panel will share responses to questions such as: What has it been like on a day to day basis? What has changed in your normal routine at home and at work? Are you scared for yourself or your family? What do you hope we learn from this pandemic?

    The Zoom-based discussion will be held at 1 pm, Friday, May 8. Register to attend.

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  • Register for upcoming Ingenuity Pathway Analysis software training

    Are you a new or existing user of Qiagen Ingenuity Pathway Analysis (IPA) software? Plan to attend a web-based, hands-on training session focusing on biological interpretation of expression data (including RNA-seq.). Using IPA, you will learn how to:

    • Format and upload your data, run an IPA core analysis and interpret the results
    • Identify pathways likely to be impacted
    • Find causal regulators and their directional effect on genes functions and diseases
    • Build pathways and make connections between proteins, compounds, diseases and more, and overlay multiple datasets on a pathway or network
    • Understand the impacted biological processes
    • Use a heat map to easily visualize trends and clusters across multiple time points or samples
    • Correlate your core analyses in IPA with thousands of other publicly available profiling data sets from OmicSoft data repository with Analysis Match

    Choose from three sessions:
    Tuesday, May 19; 9 am-noon
    Wednesday, May 20; 1-4 pm
    Thursday, May 21; 1-4 pm 

    Register online by Friday, May 15.

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  • Apply by August 4 for CTR funding

    The objective of the Indiana CTSI Collaboration in Translational Research (CTR) pilot grant program is to foster and encourage collaborations across the CTSI partner institutions and to initiate or continue translational research projects that have very strong and immediate potential to develop into larger, externally funded research programs or generate novel intellectual property (IP). Applications will be evaluated on the quality of the proposed science, as well as the application’s strength in clarifying the plan for leveraging the award toward the achievement of the two primary CTR objectives. Significant weight will be given in the review process for collaborative arrangements that have the potential to develop into a long-term partnership; one that uniquely positions the individuals to further their existing or new fields of research.

    Learn more and apply by Tuesday, August 4.

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