Alzheimer’s Association Greater Indiana Chapter announces $1 million grant for LEADS study

August 22, 2019

The Alzheimer’s Association Greater Indiana Chapter announced this week that it is funding a $1 million add-on study focusing on genetics to the Longitudinal Early-onset Alzheimer’s Disease Study (LEADS) led by IU School of Medicine. The additional funding will allow researchers to study the entire genome of all 600 participants to better understand the role of genes in the development of the disease. While genetic information will be gathered from participants at sites across the country, all of the genetic analysis will take place at IU School of Medicine.

LEADS is the largest, most comprehensive study of individuals with younger-onset Alzheimer’s disease. Led by principal investigator Liana G. Apostolova, MD, IU School of Medicine, and several co-PIs, including Alzheimer’s Association Chief Science Officer Maria Carrillo, PhD, the groundbreaking study aims to increase knowledge of the disease’s onset and progression. Because individuals with younger-onset Alzheimer’s have not yet experienced changes in the brain associated with normal aging, studying them could help lead to breakthroughs for all forms of dementia.

Read more about the grant and the LEADS study in the Newsroom.